In 2014, Ebola reached U.S. shores—a wake-up call that pandemics anywhere can threaten communities everywhere. In response, the United States with other countries and international organizations launched the Global Health Security Agenda (GHSA), a global partnership to prevent, detect, and respond to emerging diseases before they spread.

In this episode, former USAID Senior Public Health Advisor Ashna Kibria reflects on how the U.S. strengthened outbreak preparedness systems around the world and what’s at stake now that USAID is gone. From building early warning networks to partnering with governments, researchers, and the private sector, Ashna helped design programs that connected public health, agriculture, and environmental systems to stop outbreaks before they started. She also led efforts to combat antimicrobial resistance (AMR), one of the world’s most urgent and overlooked health threats.

Today, those global partnerships continue but with reduced U.S. coordination and support. As new outbreaks emerge, the world is reminded that health security depends on shared responsibility, not isolation.

Listen to learn how USAID’s partnerships once formed a quiet frontline against pandemics—and what it means now that those defenses have shifted to others.

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Dr. George Siberry, former Chief Medical Officer in USAID’s Office of HIV/AIDS, has spent his career at the heart of the global fight against HIV. A pediatrician by training, George began his journey translating for children with HIV in Baltimore and went on to help shape the President’s Emergency Plan for AIDS Relief (PEPFAR) approach to prevention, treatment, and care around the world. In this conversation, he reflects on the evolution of HIV and the programs created to fight it—from stigma and isolation to people-centered health—and what it takes to build systems that strengthen communities and improve health outcomes rather than treating diseases in isolation.

As USAID’s dismantling leaves critical partnerships fractured and PEPFAR’s future uncertain, George speaks candidly about grief, loss, and the work of rebuilding trust. He makes a powerful case for why America’s investments in global health were never just acts of charity—they were expressions of diplomacy, innovation, and shared humanity.

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Migration begins long before someone reaches a border — in the loss of stability, opportunity, and trust that makes it impossible to stay.

For decades, USAID helped address those root causes by strengthening democratic institutions, supporting communities, and building stability before crises took hold. It was one of the few agencies designed to prevent displacement rather than respond to it.

In this clip, Jeremy Williammee, former USAID Director of Democracy and Governance for El Salvador and Central America, reflects on what happens when that work disappears.

Watch the full episode to hear our conversation.