When IVF transfers fail, it can be difficult to know what to investigate next and which treatments might actually help. So what happens when an embryo doesn't implant, and what does the evidence tell us?

In this episode of Fertility Untamed, Dr Sylvia Ross, Dr Rebecca Mackenzie Proctor and Dr Devini Ameratunga discuss recurrent implantation failure, exploring why IVF doesn't always result in pregnancy and how to approach the next steps.

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Episode topics include:
- What recurrent implantation failure means
- How age and embryo quality affect pregnancy chances
- When further fertility investigations are appropriate
- The evidence behind endometrial receptivity testing (ERA)
- The role of the uterine microbiome, chronic endometritis and PRP
- Natural killer cells and immune-related fertility treatments
- The importance of weighing treatment benefits against risks
- How progesterone levels may influence IVF outcomes

What happens after a failed embryo transfer?
The doctors explore the emotional, physical and financial challenges of repeated unsuccessful transfers, why more testing isn't always better, and how to make informed decisions based on individual circumstances and the available evidence.

Fertility Untamed is hosted by three reproductive endocrinologists discussing fertility, reproductive health and the questions that come up when you're trying to build a family.

#IVF #Infertility #Fertility #EmbryoTransfer #FertilityUntamed

Being diagnosed with adenomyosis can be confronting, especially when you're already navigating fertility challenges. But what does an adenomyosis diagnosis actually mean for your chances of getting pregnant?

In this episode of Fertility Untamed, Dr Rebecca Mackenzie Proctor, Dr Sylvia Ross and Dr Devini Ameratunga discuss adenomyosis, sometimes described as the “evil sister” of endometriosis, and what we currently know about its relationship with fertility.

Episode Topics include:

• What adenomyosis is and how it's diagnosed
• Symptoms of adenomyosis
• The connection between adenomyosis and endometriosis
• Whether adenomyosis can affect natural fertility
• What adenomyosis means for IVF and embryo implantation
• Current treatment options and why the evidence is still evolving
• Whether treatments such as hormonal suppression can improve fertility outcomes
• When surgery may or may not be considered
• Why the severity of adenomyosis matters
• The most important thing to remember after receiving a diagnosis

Most importantly, an adenomyosis diagnosis does not mean you can't get pregnant. The doctors discuss why the condition needs to be considered as part of the bigger fertility picture, rather than something to automatically catastrophise

Fertility Untamed is hosted by three reproductive endocrinologists discussing fertility, reproductive health and the questions that come up when you're trying to build a family.

#Adenomyosis #Fertility #Infertility #IVF #Endometriosis #FertilityUntamed

What is hypothalamic hypogonadism? What causes women to lose their periods or have really long cycles? And how can we get your brain to kickstart communication with your ovaries again so you can get pregnant? In this ep, we also share Rebecca’s personal story of hypo-hypo, and how tackling her high-exercise, high-stress lifestyle was a big part of her journey to pregnancy success.

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You wouldn't run a marathon without training. So why do we go into trying to grow an entire human being without preparing a little first? In this episode we discuss all the steps you and your partner can take before pregnancy to get in optimum health for the journey ahead. From preconception tests to supplements to how to keep your relationship and stress levels from suffering during infertility, we're helping you get prepped for parenthood.

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Unexplained infertility is a hard road to travel. And is it really unexplained, or have we just not found the cause yet? In this episode, we discuss how we might diagnose this complex condition better, when laparoscopy and tubal testing can be helpful, and whether IVF over IUI for these patients is likely to deliver a significantly better result. Also, is DNA fragmentation testing really worth it?

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You've probably heard of gut microbiome, but did you know that your vagina has its own microbiome, and that it contains almost 10% of your body's total bacteria? I this ep, we're talking about how an imbalance of that bacteria can negatively impact your fertility, how we might test for that, and what steps you might take to restore balance. Naturally, we'll be talking probiotics, and ending with Rebecca's entertaining detour into, drumroll...vaginal microbiome transfers. Who wants to go first?

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Egg freezing is no longer experimental—it's an empowering option for people planning for the future. In this episode, we unpack the science behind egg freezing, who it's right for, and the social and emotional realities behind the growing trend. From survival rates to societal expectations, we offer clinical insight with compassion and clarity. Whether you're considering egg preservation or simply curious, this conversation brings facts and perspective to the forefront.

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In our PCOS episode we scaffold our conversation around Sylvia’s personal experience of infertility with PCOS. We’ll dig into the changing science on diagnosis, bust some pervasive myths, and talk through a range of treatment options and lifestyle changes that can help you get pregnant. This is such a complex topic, and we’re here to break it down for you in a way that’s positive, evidence-based...and at times, even a little funny.

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