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Multiple Myeloma Advances: Dr. Adeel Khan on New Treatments, CAR-T, and AI in Research

Season eight of Villages Vitality Life: Senior Life Unscripted features host Mike Roth interviewing Dr. Adeel Khan, a hematologist-oncologist and epidemiologist at UT Southwestern and director of myeloma epidemiology research and a monoclonal gammopathy precursor clinic. Khan explains multiple myeloma as a plasma cell cancer common in older adults (median onset 69) and notes rising prevalence as patients live longer, with median survival improving from about three years in the 1990s to over nine to ten years today. He outlines treatment evolution from older chemotherapies to targeted drugs and newer immunotherapies, including CAR-T (ide-cel and cilta-cel), citing 2025 ASCO data suggesting some long-term remissions that may be curative. They discuss AI analyzing genomic data, unclear prevention and risk patterns, possible benefits of plant-based diets, early MGUS/GLP-1 data, and how to contact UT Southwestern (214-648-3111).

00:00 Season 8 Welcome
00:39 Meet Dr Adeel Khan
01:46 Why Blood Cancers
03:13 What Is Myeloma
05:04 Treatment Breakthroughs
07:25 Immunotherapy And CAR T
10:41 Long Term Remission Stories
11:38 Sponsor Health Tip
13:19 AI And Genetics Research
15:09 Risk Factors And Prevention
17:04 Diet And GLP 1 Questions
18:56 Clinic Contact Info
20:11 Final Thoughts And Sign Off

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Open Forum in The Villages, Florida is Produced & Directed by Mike Roth
A new episode will be released most Fridays at 9 AM
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Bill Paddock on Voices, Improv, and Finding Comedy in Retirement at The Villages

Season eight of Villages Vitality Life: Seniors Life Unscripted opens with host Mike Roth interviewing Villages resident Bill Paddock, a retired Bureau of Prisons correctional officer and former Marine who moved from Pennsylvania to The Villages to be near family. Paddock describes how Looney Tunes voice actors (especially Mel Blanc) sparked his interest in character voices and comedy, and how early attempts at standup were derailed after realizing a headliner had recently used similar “different laughs” material, keeping him offstage for nearly 20 years. Though he considers himself introverted, he enjoys performing for unfamiliar audiences and shares a Marine Corps prank story and a radio improv character, “Bobby with an eye,” including a parody Sinatra-style song. Roth explains key improv rules and invites Paddock to local Monday sessions; Paddock plans a voice-driven podcast, Mad Dog Comedy, aiming for release by Christmas.

00:00 Season Eight Kickoff
00:40 Meet Bill Paddock
01:12 Why The Villages
01:33 Cartoons Spark Comedy
02:09 Voices and Improv
04:37 Finding the Funny
05:13 Military to Corrections
06:06 Okinawa Phone Call Win
10:01 First Standup Set Flop
12:40 Alzheimers GLP One Update
14:20 Introvert on Stage
15:51 Improv Rules Basics
16:41 Make Partners Shine
16:54 No Mistakes In Improv
17:24 Why Improv Beats Script
17:41 Show Night Highlights
18:08 Radio Improv Origins
18:56 Bobby With An Eye
19:39 Sinatra Parody Clip
23:11 Prince William Aftermath
24:03 Retirement And Pickleball Pressure
25:16 Villages Club Culture
26:58 Tap Shoes Mixup
27:39 Mad Dog Comedy Podcast
28:49 Closing Thanks And Supporters

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Open Forum in The Villages, Florida is Produced & Directed by Mike Roth
A new episode will be released most Fridays at 9 AM
Direct all questions and comments to mike@rothvoice.com

If you know a Villager who should appear on the show, please contact us at: mike@rothvoice.com

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Vitalic Health: Transforming Senior Care with AI Technology

How Vitalic Health Uses AI and Clinicians to Identify and Treat Undiagnosed Depression in Seniors

Season eight of Villages Vitality Life: Senior Life Unscripted introduces a new format featuring leaders and resources relevant to seniors in and around The Villages, Florida. Host Mike Roth interviews Vitalic Health co-founders Ben Gardner and Michelle Hoy about an AI-enabled program that screens Medicare Advantage members for depression and connects those who screen positive to immediate virtual care. Michelle explains that AI voice agents, texting/email, and timing optimization support outreach while preserving patient choice to speak with a human clinician. They discuss CMS requirements for annual depression screening in Medicare Advantage, the impact of undiagnosed depression alongside chronic conditions, barriers and stigma that lead to false negatives, and Vitalic’s “warm handoff” to coaching, therapy, and medication support via telehealth. They also cover suicide-risk screening (PHQ-9), crisis guidance including 988, and how ACOs in traditional Medicare may partner similarly. Contact details for Vitalic Health are provided.

00:00 Season Eight Kickoff
00:37 Meet Vitalic Founders
01:35 How AI Screening Works
03:01 Medicare Screening Mandate
05:00 Beyond Screening to Care
06:10 Why Seniors Avoid Help
07:19 Traditional Medicare and ACOs
10:32 Telehealth Warm Handoff
11:52 Alzheimers Tip Break
12:55 Caller ID and Voicemail
13:43 AI Voice Script and Learning
15:38 Honest Answers and Stigma
16:36 Real Patient Turnaround Story
18:35 What Families Can Do
19:22 Suicide Risk and Intervention
21:53 How to Reach Vitalic
23:59 Final Thoughts and Signoff

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Open Forum in The Villages, Florida is Produced & Directed by Mike Roth
A new episode will be released most Fridays at 9 AM
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Dr. Hany Demian on AI, Wearables, and Personalized Longevity Medicine for Seniors

Host Mike Roth launches Season 8 of Villages Vitality Senior Life Unscripted and interviews Dr. Hany Demian, founder and CEO of Praesentia Healthcare and CEO/owner of BioSpine Institute, about how AI and wearable data can shift care from reactive to predictive, personalized intervention. Demian explains using continuous metrics (sleep, stress, temperature, EKG, activity) combined with lab testing (18 blood markers, hormones, supplements, and organ-age testing) to identify risk and guide habit changes, nutrition, supplements, and lifestyle. He challenges the idea that aging must be endured, describing aging as driven by cellular energy decline and outlining regenerative approaches (exosomes, peptides, stem cells, NAD, therapeutic plasma exchange, intermittent fasting). He emphasizes sleep, exercise/strength training (including home programs), diet/protein, and regular checkups, discusses joint health and warmups to prevent injury, shares cautious optimism on stem cells, explains peptide use, and provides contact details via DrDemian.com, including virtual testing and follow-up.

00:00 Season Eight Kickoff
00:39 Meet Dr Demian
02:12 Wearables Data Problem
03:51 AI Personalized Coaching
04:57 Testing And Age Markers
05:19 Clinics And Locations
06:00 Myths About Aging
06:43 Reversing Aging Basics
07:44 Regenerative Protocols
08:29 Timeline And Consistency
10:07 Foundations Sleep Exercise Diet
11:45 Gym Alternatives At Home
12:24 Sorting Real Treatments
14:02 Ghost Cholesterol Warning
15:33 Key Aging Biomarkers
16:50 Sleep Diet Walking
19:33 Avoiding Joint Replacements
20:48 Warmup Matters
23:45 Stem Cells and Peptides
27:24 Aging Optional Book
28:20 Wrap Up and Supporters

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Open Forum in The Villages, Florida is Produced & Directed by Mike Roth
A new episode will be released most Fridays at 9 AM
Direct all questions and comments to mike@rothvoice.com

If you know a Villager who should appear on the show, please contact us at: mike@rothvoice.com

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Broadway Unplugged: Inside Shitzprobe's Improvised Musicals

Shitzprobe: Bringing Fully Improvised Broadway-Style Musicals to Florida and Beyond

Host Mike Roth opens Season 8 of Villages Vitality: Senior Life Unscripted and interviews Brooklyn-based musical improv performers Kiki Mikkelsen and Adrien Pellerin of Shitzprobe (touring as “The Improvised Broadway Musical”). They discuss their backgrounds, how the show was created to be a fully improvised musical rather than improv with songs, and the origin of the name as a play on the theater term “sitzprobe.” Mike recounts discovering them at an improv festival and notes their canceled Villages appearances, discussing promotion and ticketing, and suggests the Orange Blossom Opry as a venue. The guests describe their Sarasota run at Florida Studio Theatre (audience-suggested titles, improvised characters, plot, songs, lyrics, and dance), typical cast and band setup, long-term goals for off-Broadway/Broadway or West End, and how to follow/support them via shitzprobe.com, social media, and Patreon, plus Florida workshops April 21–23 ahead of shows April 24–25.

00:00 Season Eight Kickoff
00:40 Meet Kiki and Adrien
01:46 What Is Adult Swim
02:30 Villages Show Cancellations
04:46 Orange Blossom Opry Idea
05:49 Origins of Shitzprobe
07:38 Name Meaning Shitzprobe
09:07 Future of Improv Musicals
10:40 Florida Studio Theater Preview
12:06 Cast Band and Revenue
13:38 Alzheimers Tip Break
15:25 Improv Song About Villages
19:58 Roadmap to Broadway
21:43 Where to Follow Support
23:41 Workshops Dates and Details
25:12 Hotels and Booking Venues
26:24 Thanks and Closing Credits

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Open Forum in The Villages, Florida is Produced & Directed by Mike Roth
A new episode will be released most Fridays at 9 AM
Direct all questions and comments to mike@rothvoice.com

If you know a Villager who should appear on the show, please contact us at: mike@rothvoice.com

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Premier Garage Condos: Quality, Community, and Investment with Dave Anthony

Premier Garage Condos Near The Villages: Dave Anthony on Climate-Controlled, Secure Storage and Hobby Space

In Season eight of Villages Vitality Life: Seniors Life Unscripted, host Mike Roth interviews developer Dave Anthony, who began developing communities in the early 1980s in Punta Gorda and later designed higher-quality garage condos after seeing early, lower-ceiling, smaller models. Anthony explains why he expanded near The Villages after customers requested it, and details features of Premier Garage Condos, including mini-split climate control, R-30 roof insulation, insulated Clopay doors with hurricane bars, block-and-rebar structural walls, 18-foot ceilings for mezzanines, 100-amp service with multiple outlets, high-bay LED lighting, phone-enabled access, gated entry, cameras, and common restrooms (with optional bath prep where sewer is available). He notes strict HOA rules for personal use only, discusses unit sizes (starting 24x52), lift and mezzanine coordination, sales progress on the 37-unit Leesburg project, and provides his contact information and website.

00:00 Season 8 Kickoff
00:42 Meet Developer Dave
01:13 Why Garage Condos
01:46 Design Upgrades That Matter
02:39 Why Build Near The Villages
03:06 Climate Control And Insulation
04:06 Storm Ready Construction
05:09 Bathrooms And HOA Costs
06:57 Leesburg Site And Expansion
07:50 Unit Sizes And Mezzanines
09:23 Car Lifts And Buildouts
10:29 Standard Features And Smart Access
11:35 Security Cameras And Restrooms
13:07 Alzheimers Tip Break
14:07 Condo Ownership Vs Renting
15:13 HOA Rules And Private Use
16:24 Branding And Project Phases
18:09 Sales Update And Timeline
19:16 Fencing Lighting And No Windows
20:14 Hobbies Washing And Door Specs
22:57 Cooling Performance And Humidity
24:19 Resale Value And Flood Elevation
25:27 How To Contact Dave
27:03 More Than Storage Lifestyle
27:57 Wrap Up And Supporters

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Open Forum in The Villages, Florida is Produced & Directed by Mike Roth
A new episode will be released most Fridays at 9 AM
Direct all questions and comments to mike@rothvoice.com

If you know a Villager who should appear on the show, please contact us at: mike@rothvoice.com

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Behind The Stooges in The Villages: Wayne Richards

Wayne Richards on Bringing ‘The Three Stooges Move to The Villages’ to the Stage

Mike Roth introduces Season 8 of Villages Vitality Life: Senior Life Unscripted and interviews Villager Wayne Richards about his music-industry background and local theater work. Richards discusses his new comedy play, The Three Stooges Move to The Villages, explaining its premise (the Stooges struggle to separate their on-stage behavior from real life), its shift from an earlier title, and its intended mix of humor and heart. He shares performance dates and venues in May (Hacienda May 1, Lake Miona May 8, and Rohan May 11 and 15) and directs listeners to ActingOutTheaterClub.com for times and tickets. Richards describes the cast playing Moe (Howard Tolman), Curly (Alan Rosenchin), and Larry (Fred Solano), plus supporting characters, minimal sets across multiple theaters, and some flexible, improv-like moments. The conversation also includes light banter about The Villages, Chicago, and Portillo’s.

00:00 Season 8 Kickoff
00:49 Palm Trees and Weather
01:31 Wayne Music Career
02:27 New Show in Villages
03:01 Story and Premise
04:40 Title Change Explained
05:31 Dates Tickets Venues
06:32 Chicago Food and Beer
07:56 Show Length Format
09:39 Alzheimers Research Tip
10:49 Meet the Stooges Cast
13:25 Fountain of Youth Twist
14:25 Stooges In The Villages
14:38 Meet The Supporting Cast
15:50 Minimal Set Big Focus
16:20 Sound Mic Strategy
17:35 Scripted With Surprises
18:46 Director Onstage Bits
20:14 Stooges Film Restorations
22:00 Alligator Stage Gag
22:59 Encore And Future Plans
26:29 Tickets And Final Laughs
27:52 Show Wrap And Credits

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Open Forum in The Villages, Florida is Produced & Directed by Mike Roth
A new episode will be released most Fridays at 9 AM
Direct all questions and comments to mike@rothvoice.com

If you know a Villager who should appear on the show, please contact us at: mike@rothvoice.com

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Breaking the Silence: Turning Embarrassing Health Moments into Advocacy & Hope

Paige Golden on HPV Prevention, Bathroom Access Rights, Humor, and Disability Insurance Pitfalls

Mike Roth opens Season 8 of Villages Vitality Life, Seniors Life Unscripted, featuring conversations with leaders and seniors-focused experts in and around The Villages, Florida. Guest Paige Golden, a former book publicist and medical sales professional turned humorist and HPV/cancer awareness advocate, shares her 10-year survival from anal cancer and discusses the rise of this rare cancer, HPV’s role in multiple cancers, and the HPV vaccine’s history, age expansion to 45, and prevention impact (noting some cases are non-HPV related). Paige explains using humor and storytelling to reduce shame around gastrointestinal disorders, describes creating a character (“Sharty”) and collecting “shart” stories/poetry, and promotes a restroom access bill and bathroom access cards available in 20 states (not Florida), urging listeners to contact lawmakers. She also warns about limitations and taxation issues in employer-paid long-term disability insurance versus private policies, outlines her plan to form a foundation and a book project (“But of the Joke”), and directs inquiries through Mike at mike@rothvoice.com.

00:00 Season Eight Kickoff

00:52 Meet Paige Golden

01:49 Anal Cancer and HPV

03:24 HPV Vaccine Facts

04:49 Humor and Shart Stories

06:58 Restroom Access Bill

08:28 Advocacy Through Storytelling

10:28 AI and The Villages Projects

12:08 Foundation and But of the Joke

13:47 Ghost Cholesterol Tip

15:07 Sharty Character and Haikus

17:21 Employer Disability Insurance

22:03 How to Contact Paige

23:06 Final Reflections and Wrap

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Open Forum in The Villages, Florida is Produced & Directed by Mike Roth
A new episode will be released most Fridays at 9 AM
Direct all questions and comments to mike@rothvoice.com

If you know a Villager who should appear on the show, please contact us at: mike@rothvoice.com