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Multiple Myeloma Advances: Dr. Adeel Khan on New Treatments, CAR-T, and AI in Research

Season eight of Villages Vitality Life: Senior Life Unscripted features host Mike Roth interviewing Dr. Adeel Khan, a hematologist-oncologist and epidemiologist at UT Southwestern and director of myeloma epidemiology research and a monoclonal gammopathy precursor clinic. Khan explains multiple myeloma as a plasma cell cancer common in older adults (median onset 69) and notes rising prevalence as patients live longer, with median survival improving from about three years in the 1990s to over nine to ten years today. He outlines treatment evolution from older chemotherapies to targeted drugs and newer immunotherapies, including CAR-T (ide-cel and cilta-cel), citing 2025 ASCO data suggesting some long-term remissions that may be curative. They discuss AI analyzing genomic data, unclear prevention and risk patterns, possible benefits of plant-based diets, early MGUS/GLP-1 data, and how to contact UT Southwestern (214-648-3111).

00:00 Season 8 Welcome
00:39 Meet Dr Adeel Khan
01:46 Why Blood Cancers
03:13 What Is Myeloma
05:04 Treatment Breakthroughs
07:25 Immunotherapy And CAR T
10:41 Long Term Remission Stories
11:38 Sponsor Health Tip
13:19 AI And Genetics Research
15:09 Risk Factors And Prevention
17:04 Diet And GLP 1 Questions
18:56 Clinic Contact Info
20:11 Final Thoughts And Sign Off

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Open Forum in The Villages, Florida is Produced & Directed by Mike Roth
A new episode will be released most Fridays at 9 AM
Direct all questions and comments to mike@rothvoice.com

If you know a Villager who should appear on the show, please contact us at: mike@rothvoice.com