In this insightful episode of the Venture Capital Podcast, hosts Jon Bradshaw and Peter Harris are joined by Max Marchione, CEO and co-founder of Superpower.com, and Dr. John Dayton, MD, MBA, a healthcare innovator and venture partner. Together, they explore the evolving landscape of health technology and data intelligence, focusing on how cutting-edge biomarker analysis and AI-driven insights are reshaping disease prevention and personalized care.

Max shares his vision of building a healthcare system centered on enhancing human capability and longevity, emphasizing the shift from reactive treatment to proactive prevention. Dr. Dayton brings his frontline experience as an emergency physician and Stanford faculty member to discuss the current challenges in healthcare, including fragmented data systems and the need for interoperability to enable comprehensive, predictive care.

The conversation dives deep into the limitations of traditional single biomarker approaches and the promise of aggregating multiple data points into comprehensive health scores, like the Superpower Score. They discuss the critical role of omics data, continuous wearable monitoring, and multimodal AI in advancing personalized medicine. Dr. Dayton highlights the importance of integrating clinical data with remote patient monitoring to improve patient outcomes and reduce hospitalizations.

Throughout the episode, the guests and hosts examine the barriers to adopting these innovations within existing healthcare reimbursement models and the potential for value-based care to drive systemic change. This episode offers a forward-thinking perspective on how technology, data, and innovation converge to create a more effective, patient-centered healthcare future.

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In this episode of the Venture Capital Podcast, hosts Jon Bradshaw and Peter Harris analyze how recent government policy shifts and economic changes are influencing the venture capital landscape and broader economy. They discuss the effects of tariffs, government spending, and regulatory uncertainty on startups and investors, highlighting concerns from founders and VCs alike about how these factors impact funding availability and business operations.

Jon and Peter explore the challenges faced by companies reliant on government contracts and grants, noting how freezes and delays can threaten runway and survival. They also examine the broader fiscal picture, including rising national debt, the potential consequences of inflation and tax hikes, and the complex balancing act governments face in cutting spending without triggering recession.

The conversation touches on real-world examples, such as illustrating how radical change can sometimes be necessary to drive growth amid adversity. The hosts debate the need for significant budget cuts versus gradual reductions and discuss the antiquated state of government technology and defense spending, considering opportunities for modernization and efficiency.

Finally, Jon and Peter share their predictions for the year ahead, weighing the short-term impacts of tariffs and the likelihood of economic downturns against the resilience of the market and potential for innovation. This episode offers a nuanced perspective on how government actions ripple through the venture capital ecosystem and what founders and investors can expect in a shifting economic environment.

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In this episode of the Venture Capital Podcast, hosts Jon Bradshaw and Peter Harris dive into one of the most critical yet often overlooked topics for startup founders: the questions you should be asking venture capitalists before taking their money. Drawing on their extensive experience, Jon and Peter discuss common pitfalls that founders face when negotiating deals, including the hidden terms in contracts that can come back to haunt a company years later.

The hosts stress the importance of doing deep due diligence on potential investors—not just their financial terms, but their character and how they handle failure. They emphasize asking tough questions about how a VC firm supports struggling portfolio companies and their philosophy on valuation and terms. Jon and Peter also reflect on the delicate balance founders must strike in pushing back while maintaining a constructive relationship.

Listeners will gain valuable insight into the realities of venture capital beyond the pitch room—the importance of understanding who is investing in your company, how VCs behave when things go wrong, and how to spot red flags early. This episode is an essential guide for founders preparing to raise capital and aiming to build a strong, lasting partnership with investors.

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Apple: https://podcasts.apple.com/us/podcast/venture-capital/id1575351789
Website: https://www.venturecapital.fm/

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