Main Topic
In this episode of Oncology Unscripted, Dr. John Marshall explores how new approaches are shaping cancer treatment decisions, from using AI to help personalize treatment for individual patients to the unexpected results of a randomized trial of adagrasib in colorectal cancer. He also examines how precision medicine may help guide treatment for patients with cancers of unknown primary.

MedBuzz
In this MedBuzz, Dr John Marshall examines the rising cost of cancer treatments and the difficult questions surrounding the value of innovation including the nearly $40,000 monthly price of daraxonrasib, and the broader challenge of balancing medical advances with access to care.

Interview
In this Candid Conversation, John Marshall, MD, and Derek Raghavan, MD, PhD, discuss the business of cancer care, including treatment costs, value, financial toxicity, incentives in oncology, and the importance of honest conversations about the benefits and burdens of treatment.

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Main Topic
In this episode of Oncology Unscripted, Dr John Marshall reflects on growing vaccine hesitancy and contrasts that with new reports that a personalized melanoma messenger RNA vaccine improved outcomes in a phase 3 study.

MedBuzz
In this MedBuzz, Dr John Marshall reflects on recent changes in prescription drug pricing and the rapid rise of GLP-1 receptor agonists, their long-term impacts, and how he handles answers to questions from patients about impacts on cancer outcomes.

Interview
In this episode of Oncology Unscripted, John Marshall, MD, speaks with evolutionary biologist Daniel E. Lieberman, PhD, author of Fed Up, about the connections between physical activity, nutrition, the microbiome, and cancer prevention.

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Main Topic
In this episode of Oncology Unscripted, Dr Marshall examines the evolving role of blood-based cancer screening and highlights new research showing how dogs may help detect early cancers from breath samples.

Alternative Data Centers, Medicine, and AI Guilt?
In MedBuzz, Dr Marshall discusses the emergence of betting on clinical trial outcomes, the rise of AI in medicine, the environmental impact of data centers, and whether growing reliance on artificial intelligence should leave clinicians with a sense of AI guilt.

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