Week 6 is here, and Brian and Brennen are getting you ready for the first two games of the NFL slate!

The guys kick things off with the latest injury news and the fantasy implications of several developing situations before turning their attention to Thursday Night Football.

Seahawks vs. Broncos: Two strong defenses, a projected low-scoring game, and some tricky fantasy decisions. Can you trust Bo Nix? Is JSN the safest play on the field? And what should fantasy managers do with Seattle's backfield?

Texans vs. Jaguars: We're heading to London for an AFC South showdown. Brian and Brennen debate Trevor Lawrence, Tyler Shough, the running backs, and the pass catchers worth starting in this international matchup.

Plus, waiver wire opportunities, injury replacements, roster management and a few fantasy frustrations along the way.

Get caught up before Thursday night and come back for the full Week 6 start/sit show!

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