Inflammation is essential for healing, but when it becomes chronic, it can quietly drive joint pain, blood sugar imbalance, autoimmune conditions, and long-term disease. In this episode of Foodie Pharmacology, Dr. Cassandra Quave speaks with Dr. Josh Redd, founder of RedRiver Health and Wellness and author of The 30-Day Inflammatory Reset, about the root causes of chronic inflammation. They discuss how ultra-processed diets, environmental exposures, stress, hormonal imbalance, and even trauma contribute to inflammatory load, and what practical steps individuals can take to support immune balance through nutrition and lifestyle change. Learn more about Josh’s work at DrJoshRedd.com

Sake sits at the intersection of fermentation science, ritual, and food culture. In this episode of Foodie Pharmacology, Dr. Cassandra Quave is joined by Dr. Eric C. Rath, professor of history at the University of Kansas and author of Kanpai: The History of Sake. Together, they explore what sake really is, how fermentation with koji mold transforms rice into alcohol, and why sake has played such a central role in Japanese ritual, everyday life, and food culture. The conversation also traces the history of home brewing, the rise of izakaya gastropubs, and the emergence of American sake as both adaptation and innovation.

In the remote Alaskan wilderness, survival is not a simple metaphor. It is an act of daily practice. In this episode of Foodie Pharmacology, Dr. Cassandra Quave reconnects with Sue Aikens, best known from National Geographic’s Life Below Zero, to talk about her memoir North of Ordinary. Broadcasting from Alaska, Sue reflects on a life shaped by abandonment, fierce independence, and learning to endure both emotional and physical extremes—from brutal winters and isolation to surviving a grizzly bear attack. This conversation explores resilience, the role of helpers (human and animal), and what it means to build a sense of self when the wilderness strips everything else away.

For decades, Alzheimer’s research has been shaped by a dominant hypothesis, enormous funding streams, and the promise of breakthrough cures. But what happens when the science itself is compromised? In this episode of Foodie Pharmacology, Dr. Cassandra Quave sits down with investigative science journalist Charles Piller to unpack the revelations behind his book Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s. We examine how image manipulation, groupthink, and institutional failures distorted the Alzheimer’s research landscape for years, shaping clinical trials, drug approvals, and patient expectations. This conversation goes beyond a single disease to examine research integrity, reproducibility, and the human cost of getting science wrong.

This week on Foodie Pharmacology, we explore the cultural, scientific, and social dimensions of kava (Piper methysticum) with Douglas La Rose, Executive Director of the Kava Coalition. We discuss kava’s roots in Pacific Island traditions, how it’s prepared, what the new AHP monograph means for safety and standards, and why this non-alcoholic beverage is gaining global interest as a pro-social, calming alternative. Douglas shares insights from his work supporting education, responsible use, and sustainable industry growth, offering a grounded look at how this plant bridges community, culture, and modern wellness.

#FoodiePharmacology #Kava #Ethnobotany #PlantMedicine #WellnessCulture #NaturalProducts #KavaCoalition

What makes ibogaine such a remarkable plant-derived compound? I sit down with Jonathan Dickinson, CEO and co-founder of Ambio Life Sciences, to explore the fascinating neuropharmacology of this alkaloid and its profound impact on the brain. Jonathan is an expert on ibogaine, with more than 15 years of experience spanning clinical care, traditional practice, and psychedelic research.

We discuss iboga’s deep cultural roots in Central and West Africa, its role in Bwiti spiritual traditions, and how modern science is uncovering its potential in treating addiction, trauma, and neurological disease. Jonathan also shares insights from his pioneering work in ethical sourcing, including the first Nagoya-compliant export of iboga from Gabon, and highlights promising studies on neuroregeneration, multiple sclerosis, and traumatic brain injury. To learn more about his work, visit https://ambio.life/

#iboga #pscyhedelic #addiction #ibogaine #naturalproduct #addiction #podcast

What if the future of egg farming could eliminate one of the industry’s most difficult animal welfare issues—male chick culling? Thanks to in-ovo sexing technology, that future is here.

This week on Foodie Pharmacology, I talk with Jasen Urena, Vice President of NestFresh, about the launch of their Humanely Hatched™ eggs—the first in the U.S. to ensure only female chicks are incubated. It’s a groundbreaking step that transforms both animal welfare and consumer choice.

Jasen shares his journey at NestFresh and how the company has been at the forefront of ethical innovation, from pioneering Non-GMO Project Verified and Regenerative Organic Certified™ eggs to introducing reusable distribution systems that cut emissions and boost traceability. We discuss the promise of regenerative agriculture, how consumer demand is reshaping food systems, and why bold moves are often the catalyst for lasting change in legacy industries.

Whether you care about sustainability, farm animal welfare, or just want to understand where your food comes from, this episode offers a hopeful look at how science and ethics can come together to change what’s on our plates.

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#animalwelfare #eggs #chickens #podcast #nestfresh

Plants are master chemists. From caffeine and nicotine to powerful drugs like colchicine, they manufacture an incredible array of molecules that defend against pests, attract pollinators, and sometimes even become lifesaving medicines for humans. But how exactly do plants build these complex compounds, and why do they make them in the first place?

This week, I sit down with Dr. Ryan Nett, Assistant Professor of Molecular and Cellular Biology at Harvard University, to explore the fascinating world of plant biosynthesis. We talk about how plants orchestrate molecular “assembly lines” using specialized enzymes, why some of the most promising medicines are so difficult to source from nature, and how advances in genetics and synthetic biology are opening new doors to sustainable drug production.

Dr. Nett shares insights from his research on alkaloids such as huperzine A, investigated for Alzheimer’s disease, and colchicine, a historic treatment for gout and inflammation. We also discuss the grand challenges of plant chemistry, from deciphering massive genomes to engineering microbes like yeast to produce rare medicinal compounds.

If you’ve ever wondered how plants turn simple building blocks into some of the most valuable medicines on Earth, you won’t want to miss this conversation! Learn more at https://www.nett-lab.com/

#botany #medicinalplants #chemistry #science #biosynthesis