Stories of unethical medical experimentation often center around the individuals who spearheaded such atrocities or highlight how patient protection laws were changed in response to the studies. But rarely do they focus on the people who fought to bring these harms to light: the whistleblower. What does it take to blow the whistle, and what does it cost? Are we all capable of blowing the whistle or is there a “whistleblower type”? What happens when there’s no one left to hear the whistle being blown? These are just some of the questions we explore in this week’s TPWKY book club episode, where I’m joined by Dr. Carl Elliott, [Professor of Philosophy at the University of Minnesota] to discuss his latest book The Occasional Human Sacrifice: Medical Experimentation and the Price of Saying No. In this profound and personal work, Dr. Elliott reflects on the drivers and consequences of blowing the whistle, interviewing whistleblowers in past scandals as well as drawing from his own experience. We may all think we’d do the right thing, but how many of us are prepared for the cost? Tune in for an enlightening conversation about medical ethics and human nature.

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At the turn of the 20th century, a severe burn was often a death sentence. Today, that is no longer the case. Over the past eighty years, burn care has undergone a profound transformation thanks to crucial advances across diverse areas of medicine, such as skin grafting, antiseptic technique, and fluid balance. In this episode, we trace how those pieces of the puzzle were integrated to bring new hope to those with severe burn injuries. But this revolution in burn care is far from over. As we discover, thrilling research in this area is blurring the lines between science and science fiction. Bioengineered skin? 3D-printed skin scaffolding? Nanoparticles? Tune in for all the exciting details!

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Burns have been a part of the human experience since our hominin relatives began controlling fire 1.5 million years ago. Until very recently, we’ve been limited in our ability to manage burn wounds with any success, having instead to rely on our body’s innate healing responses. In this episode, we delve into those repair responses, explore what makes burns different from other types of injuries, and examine how we categorize burns based on severity. On the history side of things, we take a tour through humanity’s quest to alleviate the pain and suffering caused by the near-universal experience of getting burned. Ever wondered what Hippocrates would have recommended for a burn? Or what distinguishes a second- from third-degree burn? Tune in to find out.

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