The Refill: Oral GLP-1 now on the market
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Wegovy® is now available as a once-daily pill — and that changes the conversation around obesity treatment, cardiovascular risk reduction, access, and adherence.
In this week’s Refill, we revisit our original GLP-1 deep dive and add the latest updates:
✔️ FDA approval details ✔️ Oral vs injection dosing ✔️ Clinical trial data ✔️ Cost comparisons ✔️ Side effects ✔️ Who this impacts most
Same episode. New context. Because medicine doesn’t stand still.
🎙️ Listen wherever you get your podcasts. ⭐ Rate, review & follow — new episodes drop Mondays.
#MedicalMediaMixer #GLP1 #Wegovy #ObesityMedicine #CardiovascularHealth #RefillEpisode #Semaglutide
📚 Sources- FDA Orange Book. 2026.
- Wegovy® (semaglutide) FDA Drug Label. Updated December 22, 2025.
- Wharton S, Lingvay I, Bogdanski P, et al. Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity. N Engl J Med. 2025.
- Rubino D, Abrahamsson N, Davies M, et al. STEP 4 Trial. JAMA. 2021.
- Ryan DH, Lingvay I, Deanfield J, et al. SELECT Trial. Nature Medicine. 2024.
- Schweitzer K. What to Know About the Wegovy Pill for Obesity. JAMA. 2026.
- AACE Consensus Statement 2025 Update. Endocrine Practice.
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