Couverture de The Brain After Psilocybin: Nature Journal Study Review

The Brain After Psilocybin: Nature Journal Study Review

The Brain After Psilocybin: Nature Journal Study Review

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 In this video, Entheogen Institute lead instructor and director Coeli Dwivedi MS, LPF breaks down the multimodal fMRI study that tracked brain changes at baseline, during acute effects, and at 1 day, 1 week, and 3 weeks post-session. We'll look at what the data reveals about neuroplasticity, why the integration period matters clinically, and what this means for facilitators and allied professionals supporting clients through psilocybin therapy.CHAPTERS0:00 Introduction1:21 The Research Design : Nature Journal Study 20243:56 Key Findings4:38 Impact of Mystical Meaningful Experience5:25 Clinical Implications for Facilitators6:33 Closing Thoughts and a Shout out to the Participants of the Research🔬 STUDY DETAILS:• Double-blind, placebo-controlled, crossover design• 7 participants, 18 scans each• 7-Tesla and 3-Tesla fMRI imaging• Measured functional connectivity, brain network reconfiguration, and subjective experienceKEY FINDINGS:• 2.6-fold increase in brain network desynchronization during acute experience• Significant changes in default mode network and anterior hippocampus connectivity• Brain changes remained measurable at 3-week follow-up• Individual brain changes directly predicted subjective experience intensityCLINICAL IMPLICATIONS:The 3-week post-session window is a period of heightened neuroplasticity when new neural pathways are forming and old patterns are easier to interrupt. Understanding how to support this process is essential for competent facilitation and therapeutic support.📚 Study Reference:Doss et al. (2024). "Psilocybin therapy increases cognitive and neural flexibility in patients with major depressive disorder." Nature.https://www.nature.com/articles/s4158...⚠️ EDUCATIONAL CONTENT DISCLAIMER:This video discusses peer-reviewed research and legally regulated psilocybin programs in Oregon and Colorado. This information is for educational purposes only and should not be considered medical advice. Always consult with licensed facilitator or health care providers regarding your specific needs.🔗 CONNECT WITH ENTHEOGEN INSTITUTESubscribe to Our Newsletter: https://mailchi.mp/bc97570b9ae9/subsc...Website: https://entheotraining.comApply for Training: 👉🏽 https://entheotraining.com/apply-now-1Instagram: / entheogeninstitute LinkedIn: / entheogen-institute
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