In this episode of Science in Real Time, host Carli Reyes sits down with Dr. Timothy P. Spicer, Director of Assay Development & Screening at the The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, to explore how high-content screening, phenotypic discovery, and advanced imaging are reshaping modern drug discovery. Drawing on decades of experience at the forefront of translational science, Dr. Spicer shares how the field has evolved beyond traditional screening toward data-rich, image-driven approaches that unlock deeper biological understanding.

What You’ll Hear:

• From Screening to Systems-Level Insight – Dr. Spicer’s journey through the evolution of assay development and how high-content approaches have transformed discovery.
• Defining High-Content Today – what “high-content screening” really means now—and how it’s changed over the last decade.
• Phenotypes as Decision Drivers – why phenotypic screening is resurging and how imaging enables teams to embrace biological complexity.
• AI, Automation & Reality vs Hype – where machine learning is truly impactful in imaging workflows—and where expectations still outpace reality.
• Collaboration as a Catalyst – how partnerships between academia, biotech, and technology platforms accelerate innovation.
• The Next Inflection Point – Dr. Spicer’s perspective on what the next 5–10 years of high-content screening will unlock.

🌐 Explore & Connect
Learn more about Dr. Tim Spicer’s work at UF Scripps and how advances in high-content screening and imaging are accelerating phenotypic discovery.

Have an idea for a topic or guest you’d love to hear on Science in Real Time? We’d love to hear from you!
Connect with us on the ScienceIRT website or on LinkedIn: Araceli Biosciences.

If you enjoyed this episode, don’t forget to subscribe, leave a review, and share it with a colleague interested in the future of imaging, AI, and drug discovery.

🔗 Links

• Science in Real Time: https://www.aracelibio.com/science-irt-podcast-biology-big-data/
• Araceli Biosciences LinkedIn: https://www.linkedin.com/company/araceli-biosciences/
• Dr. Tim Spicer’s LinkedIn: https://www.linkedin.com/in/timothy-spicer-5786943/
• UF Scripps Institute: https://wertheim.scripps.ufl.edu/
• Dr. Tim Spicer's Contact Information: https://wertheim.scripps.ufl.edu/profile/spicer-timothy/
• Dr. Tim Spicer's publications: https://pubmed.ncbi.nlm.nih.gov/?term=Spicer+TP&cauthor_id=39159824

In this episode of Science in Real Time, host Carli Reyes sits down with Dr. Claudia McCown, a leader in high-content screening and phenotypic discovery, to explore how imaging, automation, and AI are transforming modern drug discovery. Drawing on her work at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Dr. McCown shares how the field is evolving from traditional high-throughput screening to data-rich, image-based approaches that reveal deeper biological insight.

What You’ll Hear:

• From Throughput to Insight – Dr. McCown’s journey from classical screening approaches to high-content, image-based discovery.
• Phenotypes at Scale – how high-content screening captures complex cellular behaviors that traditional assays miss.
• AI Meets Imaging – the role of automation and machine learning in accelerating and refining biological analysis.
• Collaboration Across Disciplines – lessons from bridging academia, biotech, and technology platforms like Araceli’s Endeavor.
• The Future of Discovery – how integrated workflows will reshape drug discovery and empower the next generation of scientists.

🌐 Explore & Connect
Learn more about Dr. Claudia McCown’s work in high-content screening at UF Scripps and how collaborations with Araceli Biosciences are advancing phenotypic discovery.

Have an idea for a topic or guest you’d love to hear on Science in Real Time? We’d love to hear from you!
Connect with us on the ScienceIRT website or on LinkedIn: Araceli Biosciences.

If you enjoyed this episode, don’t forget to subscribe, leave a review, and share it with a colleague interested in the future of imaging, AI, and drug discovery.

🔗 Links

• Science in Real Time: https://www.aracelibio.com/science-irt-podcast-biology-big-data/
• Araceli Biosciences LinkedIn: https://www.linkedin.com/company/araceli-biosciences/
• Victoria Arinella (UF Scripps Intern): https://www.linkedin.com/in/victoria-arinella/
• Dr. Claudia McCown's LinkedIn: https://www.linkedin.com/in/claudia-mccown-biochem/
• Dr. Claudia McCown's publications: https://pubmed.ncbi.nlm.nih.gov/?term=McCown+C&cauthor_id=40816642
• UF Scripps Institute: https://www.scripps.edu/florida/

In this episode of Science in Real Time, host Carli Reyes sits down with Dr. Reese Findley, Senior Scientists at ViQi, to explore how machine learning is transforming the way we interpret complex biological systems. Drawing on her background in neuroscience and behavioral research, Dr. Findley shares how her work uncovering hidden behavioral states in animal models evolved into designing AI frameworks that detect subtle, high-dimensional cellular phenotypes in imaging data.

What You’ll Hear:

• From Brains to Biology – Dr. Findley’s journey from neuroscience and behavior research into AI-driven cell imaging.
• Hidden Phenotypes Revealed – how machine learning models uncover patterns in cellular data that traditional analysis may miss.
• Making AI Interpretable – why transparency and collaboration are essential for building trust between computational and experimental teams.
• Women in AI & Science – mentorship, resilience, and navigating interdisciplinary career paths.
• The Future of AI in Discovery – opportunities, ethical responsibilities, and how emerging scientists can prepare for a data-driven era of biology.

🌐 Explore & Connect
Learn more about Dr. Reese Findley and her work at ViQi, and explore how AI-powered imaging is accelerating biological insight.

Have an idea for a topic or guest you’d love to hear on Science in Real Time? We’d love to hear from you!
Connect with us on the ScienceIRT website or on LinkedIn: Araceli Biosciences.

If you enjoyed this episode, don’t forget to subscribe, leave a review, and share it with a colleague who’s curious about how AI is reshaping cell biology and drug discovery.

🔗 Links

• Science in Real Time: https://www.aracelibio.com/science-irt-podcast-biology-big-data/
• Araceli Biosciences LinkedIn: https://www.linkedin.com/company/araceli-biosciences/
• ViQi, Inc.: https://www.linkedin.com/company/viqi-inc/
• Dr. Reese Findley LinkedIn: https://www.linkedin.com/in/teresa-findley15/