The PMHNP has assumed care of a 32-year-old patient who is being managed for opioid use disorder with buprenorphine-naloxone 8.2 mg films t.i.d. The patient’s previous provider has moved out of state and no records are immediately available, the only information available is from the prescription monitoring program. The patient request to be treated with a buprenorphine-only formulation because he says that the he is allergic to naloxone. The NP considers which of the following? Choose all that apply.

A. Naloxone allergy is extremely rare and more likely any adverse reaction was due to precipitated opioid withdrawal

B. It is never appropriate to use buprenorphine without naloxone when it is being used for OUD.

C. Because the PMP shows that he has been prescribed a buprenorphine-naloxone combination for the last year is not possible that he is allergic.

D. It is easier to misuse buprenorphine without the naloxone component and the NP should evaluate for misuse.

A 27-year-old female patient presents for a follow-up appointment for generalized anxiety disorder. She has a complex history including polysubstance use disorder and borderline personality disorder, but she had been doing well. She achieved remission of her symptoms over one year ago and has been well managed on escitalopram 10 mg daily. She has been substance free for over one year, and is in therapy for her personality disorder. Today she is not feeling well. She reports some major psychosocial stressors and a brief substance relapse, but she stopped using all substances 2 days ago.

The PMHNP notes a pronounced postural and intention tremor and suspects this is due to withdrawal from which of the following substances?

A. Kratom

B. Opioids

C. Marijuana

D. Alcohol

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YouTube: https://www.youtube.com/watch?v=16Vg_4HFG1A&list=PLf0PFEPBXfq5HGfNV-GbOlYHtDwd35OeG&index=122

The PMHNP is managing a patient of Chinese ancestry with a diagnosis of bipolar disorder. The patient is currently experiencing some symptoms consistent with an early manic episode.

When considering prescribing carbamazepine, the NP considers that this patient is at particular risk for which of the following adverse effects?

A. Drug-induced hepatitis

B. Pancreatitis

C. Hypothyroidism

D. Toxic epidermal necrolysis

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YouTube: https://www.youtube.com/watch?v=5MaExNnaFDM&list=PLf0PFEPBXfq5HGfNV-GbOlYHtDwd35OeG&index=121