Dr. Darsh Shah and Dr. Altamash Raja sit down with Dr. Nisha Chellam to explore her journey from traditional internal medicine to functional medicine. Together, they discuss the “revolving door” of chronic disease, why she stopped attending supplement-driven conferences, and how she blends evidence-based care with lifestyle change. Dr. Chellam shares how she helps patients uncover the true root causes of illness and reclaim ownership of their health.

SOURCES:

00:10:00 — Discovering Functional Medicine
Institute for Functional Medicine: What Is Functional Medicine?

00:18:00 — Root Cause Medicine Explained
Cleveland Clinic: Functional Medicine Approach

00:34:00 — Functional vs. Lifestyle Medicine
American College of Lifestyle Medicine: What Is Lifestyle Medicine?

00:58:00 — Functional Labs and Data-Driven Care
PubMed: The Value of Advanced Biomarkers in Functional Medicine

01:06:00 — Metabolic Health and Insulin Resistance
American Heart Association: Understanding Insulin Resistance

01:15:00 — Redefining What “Good Medicine” Means
BMJ: Rethinking Medicine — The Movement to Redefine Care

Contact Dr. Chellam:

Linkedin | Nisha Chellam

Instagram, YouTube, X | @holisticicon

Find Us Here:

Instagram, Threads, X, TikTok | @medredefined

Thank you for listening! Let us know what you think!

Darsh and Altamash talk to Dr. Leah Houston, an emergency medicine physician turned healthcare entrepreneur, for insights on the broken physician credentialing system and how technology could restore autonomy to doctors.

TIMESTAMPS:

00:01:00 – Evercred (decentralized physician credentialing platform) evercred.com

00:04:00 – Centers for Medicare & Medicaid Services (CMS) oig.hhs.gov

00:05:00 – Relative Value Unit (RVU) definition en.wikipediaorg

00:12:00 – The Joint Commission (healthcare accreditation body) 00:14:00 – National Provider Identifier (NPI) en.wikipedia.org

00:19:00 – Interstate Medical Licensure Compact (IMLC) imlcc.com

00:28:00 – Decentralized Identity (DID) in healthcare healthdatamanagement.com

00:29:00 – Direct Primary Care (DPC) payment model https://www.healthinsurance.org/glossary/direct-primary-care/

00:39:00 – Blockchain (distributed ledger technology) explained techtarget.com

Thank you for listening!

Darsh and Altamash are back, trading thoughts on what’s been capturing their attention lately - from the tech tools boosting daily efficiency to the appeal of living more “pro-analog.” They dive into the hype and science behind ketones, unpack how GLP-1s are reshaping the way we think about food and cravings, and share insights on what it really means to find preventive, proactive healthcare today. It’s a thoughtful but approachable conversation, blending current events, health trends, and practical takeaways.

TIMESTAMPS

00:00 Introduction to Medicine Redefined

00:33 Current Events and Political Landscape

02:10 Random Show Concept and Personal Updates

02:44 Writing and Creative Outlets

06:48 Tech Tools and Apps for Efficiency

10:32 Medical Innovations: Vagus Nerve and Hydrodissection

19:48 Breathwork and Meditation Techniques

23:49 Exploring Exogenous Ketones

28:31 Understanding Brain Health and Mood Disorders

29:31 Exploring Ketone Supplements

30:52 Nootropics and Cognitive Enhancers

32:48 The Future of Social Connection

40:44 The Concept of Misogi and Mental Fortitude

42:34 GLP-1 and Obesity Treatment

49:36 Navigating Healthcare and Finding the Right Provider

SOURCES

05:12 | How and Why To Try Alternate Nostril Breathing (Cleveland Clinic)

08:47 | Buteyko vs Soma Breathing: Origins, Benefits and Differences (Buteyko Clinic International)

14:33 | OU Researchers Explore Vagus Nerve Stimulation for Multiple Conditions (University of Oklahoma)

19:55 | Exogenous Ketones: Do They Work, and Are They Safe? (Medical News Today)

24:18 | Ozempic Quiets Food Noise in the Brain — But How? (Scientific American)

27:42 | “Food Noise”: Do Weight Loss Drugs Stop It? (Health.com)

33:11 | How to Find a Medicine 3.0 Doctor like Dr. Peter Attia (Vitality / AWI Longevity Clinic)

37:40 | Embracing an Analog Lifestyle: Opt Out of Overwhelm (The Tiny Life)

41:05 | “The ‘Boring Phone’ – Gen Z Ditch Smartphones for Dumbphones” (The Guardian)

45:22 | Alfred – Productivity App for macOS (Official Site)

47:36 | OpenAI Whisper (Speech Recognition AI)