Saloni Dattani, author of the Scientific Discovery Substack and founding editor of Works in Progress magazine, joins Infinite Loops to discuss why medical innovation is often much slower than it needs to be.

We explore why so much research still begins in animal models, how poor data distorts our understanding of disease, why clinical trials are one of the biggest bottlenecks in medicine, and how better systems could help promising treatments reach patients faster.

Important Links:

Read more from Saloni here: https://worksinprogress.co/our-authors/saloni-dattani

And here: https://substack.com/@salonium

And listen to Saloni's podcast "Hard Drugs" here: https://harddrugs.worksinprogress.co/

Why has America become so bad at building housing, infrastructure, and major projects?

Brian Potter, author of The Origins of Efficiency and writer of Construction Physics, explains why prefab housing keeps failing and why there are no easy fixes to America's building problem. We discuss Katerra, California's anti-growth turn, and the deeper logic behind local opposition to growth: concentrated harms and diffuse benefits.

Important Links:

Read Brian's newsletter Construction Physics here: https://www.construction-physics.com/

Read Brian's book The Origins of Efficiency here: https://press.stripe.com/origins-of-efficiency

Learn more about Brian here: https://ifp.org/author/brian-potter