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Go Un-Pro

De : Brent W. Laartz
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 Go Un-Pro with Dr. Brent W. Laartz, MD FIDSA: Living an Unprocessed Life for Longevity and Healthspan Have you ever known that something is SO good for you that you just can't wait, but life gets in front of you and prevents you from doing it? The inaction and procrastination could occur for a variety of reasons, and we will delve into my motivations and affirmations of a healthy life from this day forward. I am starting this series of videos and articles so that I can be accountable to myself regarding the changes in my diet that I REALLY NEED to survive into my 90s without heart disease, dementia, and arthritis. And hopefully, as you follow along, you can make your own improvements that will extend your life and prevent the horrible illnesses that are heart disease, dementia, and arthritis. Can I introduce myself? I'm Dr Brent W. Laartz, and I am an Infectious Diseases physician with a Master's in Neuroscience, author, creator, and entrepreneur. I've been involved with medical education for almost all my life and have been sharing my knowledge, teaching students, patients, and other doctors as faculty of a medical school, in hospitals, and clinics around the world. I'm ashamed to admit that I have lived a life of processed foods despite knowing the facts that are stacked against me if I continue living this way. My most recent research into longevity and its connection to our diet, exercise, sleep, and mental health, all with help from our microbiome, the bacteria living in our body, has me wanting to shout this information to the masses from the rooftops! This is so important that I am going to communicate what I have learned in every forum possible. Simply put, I am not going to do it anymore, and I am going to stay accountable to myself so that I follow through with it this time. Hence, the launch of this podcast, which I have been wanting to do for quite some time now. In addition, I am also launching publicly available Master courses that will delve incredibly deeply into the science behind diet and other interventions that will help me live well into my '90s and 100s, but not just live, but REALLY live! This is the concept of Healthspan. I know there are a lot of billionaires who are prominent in the media, trying to live forever, spending millions of dollars, but I am here to prove you can do it without spending a lot of money. The interventions I am doing will cost a little more money, but my budget is to only increase expenditures by a few $100 a month. The thing is, we are so accustomed to our artificial products that we deep down believe they are good for us. Don't accept this BS from your food, expect better. Most physicians I know are not living a healthy life, and until the past 6 months, that generalization included me. If you think otherwise, let me paint the picture of a typical doctor's lounge in the hospital or the home kitchen of your local physician. Hospital kitchens use the cheapest oils, fried foods, and beef, butters with mashed potatoes, pre-manufactured eggs, mass-produced bacon, candy, and ice cream sandwiches. This is what I was eating day in and day out, working 26 days per month. My cholesterol was skyrocketing, and my weight had peaked at 165 pounds on a 5-foot-7-inch frame. Then I took stock of my life. And it was just in time, too, for my kids were graduating from high school. At least I didn't have the excuse of cleaning my kids' plates anymore. I suspect that if you are listening to this podcast, reading this article, or taking this course, you are interested in living a more unprocessed life. If you are like me, you have reached a point in your life where you realize your health could be at a tipping point. I was lulled into thinking I was living a healthy life because I exercised and ate right some of the time. But that delusion could not have been further from the truth. I was drinking alcohol at least a few days per week, drank sodas at least a few days a week, and ate eggs, bacon, buffalo wings, cheeseburgers, candy half the week. As a physician, I should have known better. If you grew up similarly to me at the beginning of the downfall of America into the ultra-processed society, then your mother initially cooked dinners that contained whole foods most of the time. However, she also fell into the trap of the simpler life of the American family, spending less time cooking and more time eating macaroni and cheese, canned beef stew, box cereals with added sugar, and chocolate candy bars for dessert. I found myself a few years ago at age 55. Double nickel! At 5'7", I was down from my peak height of probably 5'8" tall and 165 lb at the heaviest, and about 157 lb at the lightest. Calculate that. It is a BMI of 26 - barely, but in the overweight category. While I generally pictured myself as being relatively healthy and eating relatively healthy foods, I started to look at my pictures with a critical eye, and ooking at my friends was like looking in a mirror in both...2025 Hygiène et vie saine
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  • Week 10: A Doctor's 52 Week Journey to an Unprocessed Life

    Week 10: A Doctor's 52 Week Journey to an Unprocessed Life
    May 6 2026

    Week 10: A Doctor's 52 Week Journey to an Unprocessed Life

    Week 10 Summary: Microbiome Mastery in a Doctor's 52-Week Unprocessed Life Journey

    Dr. Brent W. Laartz

    Reflects on Paris trip (high steps, fiber via fruits/salads, minimal supplements).

    Focuses on **microbiome week**: Gut bacteria's role in health/longevity; impacts from ultra-processed foods, red meat (e.g., colibactin-producing E. coli linked to colon cancer 10-20 years pre-diagnosis); promotes plant-based/Mediterranean/MIND diets.

    Discusses inflammation/leaky gut from poor microbiota (lipopolysaccharides entering blood); personal diet: 3-4 vegan days/week, minimal red meat/dairy (some cheese), low protein + resistance training for longevity/muscle preservation.

    Ties microbiome to **five pillars** (diet, movement, sleep, plastics, connection): Fiber/pre/pro/postbiotics produce short-chain fatty acids (SCFAs like butyrate/propionate) for gut health, fitness, sleep; exercise enhances SCFA benefits; alcohol disrupts good bacteria; fermented foods > probiotics.

    Debunks myths: Fiber not "anti-nutrient"; low-protein diets (e.g., isoleucine-deficient) extend mouse lifespan 20%; avoids gym bro high-protein/carnivore/keto fads.

    Recaps progress (week 10/52): Berries daily, accountability app tracking, supplements (B12, omega-3, D, calcium), steel/glass kitchenware, olive/avocado oils, no packaged foods goal.

    **Personal updates**: Cholesterol improved; plans re-test plastics in urine post-water bottle changes; 36-48h fast weekly.

    Key Points and Decisions

    **Microbiome Health Drivers**:
    - Avoid ultra-processed/red meat → reduce colon cancer risk (screening now at 40).
    - High fiber (psyllium, inulin, raw veggies/fruits/nuts/beans) → SCFAs → healthy colonocytes, no leaky gut, better fitness/sleep.
    - Fermented foods (hummus, yogurt, sourdough) for persistent bacteria.
    - Low protein + resistance training preserves muscle in aging.

    **Diet Decisions**:
    - 4-5 vegan days/week (aim 6 by year-end); raw veggies/fruits/nuts/beans 3x/week; homemade hummus/beans; 40+ whole foods variety (berries/pineapple only fruits); 100% vegan attempt this week.
    - No red meat/dairy (cheese exception); beans 3x/week; 2 tbsp psyllium daily; more water.

    **Other Pillars**:
    - **Movement**: 20k steps goal (10k min); racket sports 1x/week (tennis for impact/upper body/connection); dog walks; resistance training.
    - **Sleep**: Rose-Thorn-Bud meditation (reframe negatives), 4-7-8 breathing, blackout room/mask.
    - **Connection**: Music class (Khan Academy), learn guitar/saxophone, poetry/painting, reconnect old friends (Thursday Throwback), language apps (French/Spanish/Italian).
    - **Plastics**: Stainless/glass pet bowls; PVA-free laundry tablets; bamboo toothbrush/toothpaste tablets; glass water dispenser.
    - **Fasting**: 36-48h weekly for autophagy/insulin reduction.

    Next Steps

    **Diet**: Hit 40 whole foods; 5 vegan days/week long-term; raw cashews; expand bean variety (black beans/rice).

    **Movement**: Racket sports (tennis courts field trip week 11); maintain running/resistance; dog walks early AM.

    **Sleep**: Daily Rose-Thorn-Bud + 4-7-8; better blackout/mask.

    **Connection/Creativity**: Khan Academy music class; instruments (bass guitar, sax); Friday poetry, Monday meditation video.

    **Testing/Monitoring**: Re-test cholesterol/apoB/Lp(a); plastics in urine after non-plastic water switch.

    **Podcast**: Week 11 field trip (tennis demo, high-impact workouts for longevity); book release post-52 weeks.

    **Accountability**: App tracking (vegan, greens/berries, exercise, fasting, beans/ferments, no sugar/soda/packaged).
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    1 h et 17 min
  • Week 9: A Doctor's 52 Week Journey to an Unprocessed Life

    Week 9: A Doctor's 52 Week Journey to an Unprocessed Life
    Apr 27 2026

    Week 9: A Doctor's 52 Week Journey to an Unprocessed Life

    Week 9 Summary: Dr. Brent Laartz's Unprocessed Journey – Paris Travel Edition

    Summary by Speaker

    Dr. Brent Laartz

    *Travel Edition (Paris/France)**: Week 9 update; praises French culture, food (organic markets, berries, strawberries, chocolate), architecture; notes smoking culture among youth.

    **5 Pillars Challenges/Adaptations**:
    - **Diet**: Mostly vegan (3-5 days/week), antioxidants (berries, dark chocolate), local produce; avoids fake meats/cheeses; plans crepes/hot chocolate (dairy-free); less alcohol, zero-alc options.
    - **Movement**: High activity (25k steps/12 miles walking, 4-mile run); preps with prior training to avoid injury; prefers walkable areas, run clubs, hiking; avoids Ubers.
    - **Sleep**: Jet lag prep (dark room, morning light, advance clock, avoid caffeine/plane sleep); cooler room, weighted blanket.
    - **Connection**: Meets locals/expats (college friend, run clubs, cafes, small tours, French classes like "French as You Like It"); avoids tourist traps/Americanized spots.
    - **Plastics/Chemicals**: Organic shops for soaps/lotions; glass water bottles (Evian); avoids hotel plastics.

    **9-Week Progress Recap**: Weight loss, better cholesterol/HbA1c (ex-pre-diabetic); berries daily, Oura ring, meal prep, supplements (Ca/D/B12/omega-3), vegan shifts, low-carb/no artificial sugars, psyllium/fiber, homemade dressings, run clubs, non-plastic home, mindfulness.

    **Personal Insights**: Stay true to local culture; health for longevity; self-worth key.

    Key Points and Decisions

    **Diet Decisions**: 3-5 vegan days (incl. travel); prioritize antioxidants/local organic (berries, dark chocolate); homemade dressings; poultry/seafood only if non-vegan; no fake vegan products.

    **Movement**: 6 days/week training (cardio/resistance); vacation exceeds routine; prep to prevent injury; join Paris run clubs (walkers welcome).

    **Sleep/Travel Hacks**: Blackout rooms, morning sunlight, clock advance, no afternoon caffeine.

    **Connection**: Local immersion (cafes, small tours/classes, expats); family cultural exposure.

    **Avoidances**: Plastics/chemicals (glass/stainless, organic products); processed foods/oils; non-stick pans; red meat/dairy excess; Ubers when possible.

    **Health Wins**: Improved metrics despite family diabetes risk; extended fasting.

    Next Steps

    Meet college friend in Paris (possible walk/Uber).

    Join Paris run clubs (20+ options).

    Take French class ("French as You Like It").

    Continue 3-4 vegan days; eat crepes/dairy-free hot chocolate.

    Weekly Zoom calls; follow/share on gonopro.com, social media (TikTok, Instagram, Facebook, Threads, Substack, YouTube/Spotify/Apple video podcasts; Brent Williams Larson MD).

    Sustain pillars for longevity; audience input welcome.
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    30 min
  • Sunday Science Testosterone 2026_04_19

    Sunday Science Testosterone 2026_04_19
    Apr 20 2026

    Sunday Science: Testosterone Therapy – Risks, Benefits & Longevity Debate

    Summary by Speaker

    Dr. Brent Laartz

    Discusses testosterone decline with age (0.4-2.6%/year, 30-50% by 50-60), low T (<250-300 ng/dL) linked to metabolic syndrome, obesity, increased mortality.

    Reviews studies:
    - Low T associated with 1.5-2.3x higher all-cause, CV, cancer mortality (2010 European Heart Journal cohort; 2011 JCEM meta-analysis).
    - Frailty mediates 35% of low T mortality risk.
    - Eunuch/castration studies (Korea, Poland, animals): 10-20% longer lifespan, but pre-puberty vs. late-life low T.
    - TRT studies: Decreased mortality if levels normalized (2012, 2015 European Heart Journal cohorts); short-term (<2-9 months) neutral/possible risk, long-term (>3 years) benefit; non-normalized TRT no benefit.

    Notes biases in cohorts (healthy user effect); no RCTs yet.

    Emphasizes N=1 individualized approach considering personal risks (e.g., prostate/heart disease).

    Key Points and Decisions

    **Low Endogenous Testosterone**: Strongly linked to higher mortality (all-cause, CV, cancer); associated with frailty, metabolic issues.

    **Castration/Eunuch Data**: Suggests lifelong low T may extend life, but not directly comparable to adult TRT.

    **TRT Evidence**: Cohort studies show mortality reduction with normalized levels (esp. long-term), but short-term CV risks possible; no definitive RCTs.

    **No Firm Decisions**: Informational only; no endorsements for/against TRT; highlights need for RCTs to resolve controversy.

    Next Steps

    **Research**: Await randomized controlled trials (RCTs) for definitive TRT mortality data.

    **Individuals**: Check testosterone/health markers regularly (yearly+); consult physicians for personalized risks/benefits; prioritize resistance training, healthy lifestyle.

    **Audience**: Seek professional medical advice; follow show on YouTube, Spotify, Apple Podcasts, social media, goonpro.com.
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    23 min
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