Couverture de Endgame with Amanda Cassatt

Endgame with Amanda Cassatt

Endgame with Amanda Cassatt

De : Serotonin
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The world is changing at an accelerating pace—Endgame is here to make sense of it. Hosted by Amanda Cassatt, founder of Serotonin, this podcast brings you conversations with the visionaries driving breakthrough technologies and shaping the future. Join Amanda as she unpacks the trends, innovations, and paradigm shifts defining our time. Where is this all going? Let’s figure it out together. Subscribe now on Apple Podcasts, Spotify, YouTube, and wherever you listen.Serotonin Economie
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    Épisodes
    • Against the Crypto Casino | Kevin Owocki
      Jan 14 2026

      What happens when crypto stops optimizing purely for profit and starts optimizing for people, planet, and long-term coordination?

      In this episode, Amanda Cassatt sits down with Gitcoin founder Kevin Owocki to discuss Ethereum’s public goods, swallowing the Green Pill, and what onchain coordination will look like in the future.

      Owocki maps the cultural fault lines inside Ethereum: the libertarian and cypherpunk roots, the rise of hyper-financialized degen culture, and the parallel effort to build something different: a regenerative ecosystem that funds public goods, sustains open source, and solves coordination failures instead of reproducing them.

      The two unpack what Green Pill really means and the choice it asks of builders, how Gitcoin funded $70 million in public goods and why grants and vibes aren’t enough anymore.


      Timestamps:

      00:00 Introduction to Regen and Degen

      02:57 The Green Pill Movement

      06:13 Public Goods in Ethereum

      09:10 Funding Challenges in the Ethereum Ecosystem

      12:07 Comparing Ethereum to Traditional Governments

      15:00 The Evolution of Public Goods Funding

      17:48 Incentive Alignment and the Tragedy of the Commons

      21:04 Building Proofs for Public Goods

      24:11 Ethereum's Unique Approach to Public Goods

      26:48 Meditations on Moloch and Coordination Failures

      29:39 Exploring Moloch and Ginsberg's Influence

      30:04 Addressing Coordination Failures in Ethereum

      34:48 The Future of Capitalism and Its Alternatives

      39:40 Balancing Different Forms of Capital

      45:03 Navigating Financial Nihilism Among Youth

      47:41 Success Stories in Building Parallel Institutions


      Subscribe to Endgame: https://www.youtube.com/@endgamepodcast

      Kevin on X: https://x.com/owocki

      Amanda on X: https://x.com/amandacassatt

      Serotonin on X: https://x.com/serotonin

      Endgame on Spotify: https://open.spotify.com/show/6iSvbKOJWoEPiAoGmiulkd

      Endgame on Apple Podcasts: https://podcasts.apple.com/us/podcast/endgame-with-amanda-cassatt/id1801809440

      Substack: https://substack.com/@UCInZsV3L1nDGoFjxoNUnPQQ

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      46 min
    • Has Crypto Become TradFi Rebranded? | Gabriel Shapiro
      Jan 7 2026

      Crypto was supposed to be the escape hatch. So why does it increasingly feel like it’s being absorbed by the very systems it set out to challenge?

      In this candid conversation, Amanda Cassatt sits down with cyberpunk crypto lawyer Gabriel Shapiro about the “fintech-ization” of crypto, where the industry stands in the post-Gary Gensler era and the fading relevance of the four-year cycle.

      Is crypto a tool for resisting power, or just a more efficient version of traditional finance waiting to be regulated into submission?

      Regulation isn’t a complete negative for the space; Gabriel believes that certain aspects, such as antitrust law, are beneficial. But while some laws age like a fine wine, others aren’t as relevant as technology evolves.

      Amanda and Gabriel also discussed KYC and how it’s evolving, zero-knowledge proofs, and what Tornado Cash did wrong.


      Timestamps:

      00:00 Current State of Crypto and Market Cycles

      02:53 The Debate on Decentralization vs. Centralization

      05:47 The Role of Government and Regulation in Crypto

      08:43 Crypto as an Alternative to Traditional Legal Systems

      11:49 The Impact of Incumbent Protection on Innovation

      15:03 The Future of Crypto in a Regulated Environment

      17:51 The Importance of Privacy and Programmability in Crypto

      26:18 The Imperative of Privacy in Crypto

      34:52 Navigating Legal Compliance and Privacy

      39:41 The Dilemma of Civil Disobedience

      46:24 The Future of KYC in Crypto

      48:40 Zero Knowledge Technology and Its Potential

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      41 min
    • Why AI Is Crypto’s Biggest ‘Competitive’ Threat | Aaron Wright
      Dec 18 2025

      Is crypto’s biggest rival artificial intelligence?

      As AI absorbs talent and capital, it’s not clear yet if crypto and AI are competing or converging but crypto’s focus on human agency may matter more than ever in an automated world.

      Amanda Cassatt is joined by Aaron Wright, crypto lawyer, former Wikia general counsel and CEO of Tribute Labs, to unpack the battle between crypto and AI and what the explosive growth of stablecoins actually means for the U.S. dollar as both institutions and corporations look to gain exposure to crypto.

      Outside of the technological battle we’re seeing, Aaron believes we’re also undergoing a structural shift that’ll see the separation of the U.S. dollar from U.S. banks. He discusses the slow erosion of smaller national currencies, and the rise of open, permissionless financial infrastructure that anyone can access. What looks incremental today may ultimately reshape who controls money and how power flows in a dollar-dominated world.

      The conversation spans across artificial intelligence, dollar hegemony, central bank authority, as well as the growing divide between institutional crypto and the onchain “trenches.”


      Timestamps:

      00:00 – Cold Open: Stablecoins and the End of Dollar Hegemony

      05:00 – Splitting the Dollar from the Banks

      10:00 – Do Stablecoins Weaken Central Banks?

      15:00 – Should Local Currencies Even Exist?

      20:00 – The Paradox of American Decline

      25:00 – Regulation, Law, and Crypto’s Lost Years

      30:00 – Institutional Crypto vs. the Trenches

      35:00 – Is Crypto Still About Technology?

      40:00 – AI vs. Crypto

      45:00 – Open Systems, Wikipedia, and Internet Decay

      50:00 – KYC, Surveillance, and Enshittification

      55:00 – Identity, Reputation, and ZK Proofs

      1:00:00 – Crypto’s Endgame: Human Agency


      Resources:

      Follow Aaron Wright @awrigh01 https://x.com/awrigh01

      Learn more about Aaron's work: https://papers.ssrn.com/sol3/cf_dev/AbsByAuth.cfm?per_id=2373233


      Subscribe to Endgame: https://www.youtube.com/@endgamepodcast

      Amanda on X: https://x.com/amandacassatt

      Serotonin on X: https://x.com/serotonin

      Endgame on Spotify: https://open.spotify.com/show/6iSvbKOJWoEPiAoGmiulkd

      Endgame on Apple Podcasts: https://podcasts.apple.com/us/podcast/endgame-with-amanda-cassatt/id1801809440

      Substack: https://substack.com/@UCInZsV3L1nDGoFjxoNUnPQQ

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      45 min
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