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Daily Value

Daily Value

De : William Wallace Ph.D.
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Daily Value is a podcast examining the biological foundations of human function. Hosted by Dr. William Wallace, episodes explore nutrition, supplementation, and related health topics through the lens of biochemistry, physiology, and human evidence


© 2026 Daily Value
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    Épisodes
    • The New Dietary Guidelines Controversy — Explained
      Jan 12 2026

      PREFACE: This is an explanation of the debate the guidelines have stimulated. It references the data used to rationalize the guidelines and the data used to oppose them. There is nothing here that was not cited by the new or old guidelines. For a full review, please see my website.

      The 2025–2030 Dietary Guidelines introduced changes that have caused confusion, disagreement, and strong reactions across nutrition and public health. In this episode of Daily Value, we walk through what actually changed, what didn’t, and why, explaining the evidence standards, policy constraints, and scientific disagreements that shaped the guidelines. The goal isn’t to tell you what to eat, but to help you understand how national nutrition policy is made, and why this cycle looks different from those before it.

      00:00 Introduction to the Dietary Guidelines Controversy

      01:16 Understanding the Dietary Guidelines

      02:48 The Shift in Scientific Foundations

      07:23 The Diet-Heart Hypothesis Debate

      11:36 Reevaluating Full-Fat Dairy

      15:15 The Ongoing Debate and Its Implications

      19:28 Conclusion and Further Reading

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      13 min
    • Fish Oil, Oxidation, and the Truth About “Rancidity”
      Jan 5 2026

      Omega-3 supplements are at the center of a controversy regarding their oxidation levels and potential harm. This presentation addresses the gap between claims of harm and the available human data, explaining how oxidation is measured and interpreted.

      00:00 Introduction to Omega-3 Supplements

      00:49 Understanding Oxidation in Fish Oil

      01:10 Measuring Oxidation: Peroxide, Anisidine, and Totox Values

      01:50 The Flavoring Problem in Oxidation Testing

      02:46 Market Surveys and Oxidation Failures

      04:08 Do Oxidation Standards Correlate with Human Harm?

      04:30 Clinical Trials on Oxidized Fish Oil

      06:54 Regulatory Perspectives on Oxidation and Safety

      07:57 Summary and Takeaways

      09:08 Conclusion and References

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      9 min
    • A Nutrient Mixture That Tunes Brain Signaling
      Dec 12 2025

      Nutrients are usually studied in isolation, yet synapses don’t operate that way. This episode examines research showing that coordinated nutritional inputs can reshape synaptic proteins and neural firing patterns (effects that isolated inputs fail to produce). The shift isn’t about stronger signaling, but more organized signaling within brain circuits.

      The goal: explain why biological systems respond to combinations rather than singles, how coordinated inputs influence synaptic receptors, protein synthesis, and network synchronization.

      00:00 Introduction to Neural Circuit Malfunctions

      00:39 Understanding Neural Communication

      01:38 Nutrient Interventions in Neural Circuits

      02:57 Research Findings on Nutrient Mixtures

      04:37 Mechanisms of the Mixture

      06:33 Practical Implications and Dietary Recommendations

      09:01 Conclusion and Final Thoughts


      PMID: 41329641

      PMID: 38498094

      PMID: 40910091

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      9 min
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