House on Haunted Hill: Resurrection is a contemporary reimagining of the iconic Vincent Price horror film. After serving a 20-year sentence for his wife's murder in the notorious House on Haunted Hill, Frederick Loren decides to host another haunted house party with a sinister agenda—to expose several self-proclaimed psychics as frauds. Seven individuals, each harboring their own flaws, eagerly accept Loren's invitation, enticed by the promise of a $100,000 prize if they survive the night.

Unbeknownst to the guests, the mansion's previous owner, Watson Pritchard, firmly believes in its haunted nature, and his convictions prove chillingly accurate. The malevolent spirit of Inquisitor Torquemada, along with his bloodthirsty henchmen, awakens from its slumber after years of dormancy, fixating its supernatural wrath on the unsuspecting guests.
Soon after their arrival, the guests discover the sinister truth—they are trapped inside the house until morning, with no electricity, internet, or cellphone reception. The windows are barred, and the doors are impenetrable steel. Unsettling events quickly unfold, with guests vanishing one by one in the labyrinthine corridors of the haunted house.

As the vengeful ghosts grow increasingly active, the remaining guests embark on a desperate quest to find a means of escape, all while Frederick Loren's hidden cameras capture the night's terror, intending to expose the fraudulent psychics. But as the house's sinister forces close in, survival takes precedence over unveiling the truth, and the guests must confront their deepest fears and unravel the secrets that bind them to the House on Haunted Hill.