Abstract: Organizations frequently attribute implementation failures and adaptation challenges to cultural misalignment or inadequate incentives. However, mounting evidence from organizational behavior, network science, and comparative institutional research suggests that formal structure—specifically hierarchical configuration and decision-making architecture—exerts greater influence on employee behavior than culture change initiatives or compensation redesign. This article synthesizes research on organizational modularity, structural determinants of behavior, and ecosystem emergence to argue that flattening hierarchies and redistributing authority to operational edges fundamentally rewires information flow, decision velocity, and collaborative patterns. Drawing on empirical cases from manufacturing, technology platforms, and healthcare delivery across North America, Europe, and East Asia, we demonstrate that structural reconfiguration enables adaptive behaviors that resist cultivation under traditional pyramid architectures, regardless of cultural interventions. The analysis concludes with evidence-based frameworks for structural redesign that prioritize network density, decision proximity to information sources, and cross-boundary coordination mechanisms as foundational prerequisites for organizational agility.