By the early 1990s, Colombia's Cali cartel had become what the former head of the DEA Thomas Constantine referred to as "the biggest and most powerful crime syndicate in history." Responsible for nearly 85% of the cocaine that reached US soil and 90% worldwide, they were untouchable. They brazenly corrupted thousands of Colombian authorities and government officials, even buying the outcome of the 1994 presidential election.

That same year, the DEA sent young operatives Chris Feistl and Dave Mitchell to Colombia with one formidable task: help Colombian authorities take down the ruthless leaders of the brutal Cali cartel. Not any easy job for two men who looked more like tall California surfers than DEA agents. Many of their colleagues feared for their safety, openly questioning their ability to blend in. Their almost three-year journey would lead them from the bureaucratic halls of the US Embassy to the violent streets of Cali and deep into its rural sugar cane fields, keeping them on high alert day and night as they dodged deadly cartel assassins and battled the unprecedented corruption within Colombia's security forces. Over time, their relentless efforts began to slowly degrade the cartel's defenses and weaken its infrastructure, leading to a demise many never even thought possible.