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The Smartest Doctor in the Room

The Smartest Doctor in the Room

By: Dean Mitchell
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Summary
 A combination of a lively, personal and in-depth interview with top healthcare specialists. The average listener may not have access to the expert medical advice athletes, actors and CEO’s have today, but on this show, they will learn the key facts to know about any health conditions that they or their family deal with. Hosted by Dr. Dean Mitchell. https://www.mitchellmedicalgroup.com/Copyright Dean Mitchell Hygiene & Healthy Living Nature & Ecology Science
Episodes
  • Ep. 249 - The Mount Sinai Long COVID Clinic's Update on Care

    Ep. 249 - The Mount Sinai Long COVID Clinic's Update on Care
    10 Nov 2026
    Long COVID does not have one cause. Different patients have different drivers, including autoantibodies, persistent spike protein, herpesvirus reactivation, and mast cell activation, which is why the guiding rule at Mount Sinai's long COVID clinic is to treat the drivers, not the symptoms.

    Dr. Dean Mitchell talks with Dr. David Putrino, a neuroscientist and the Nash Family Director of Mount Sinai's Cohen Center for Recovery from Complex Chronic Illness, about what his team has found and which treatments are now being tested.

    In this episode:
    • How the Mount Sinai long COVID clinic started, and how patients are evaluated for fatigue, post-exertional malaise, and sleep
    • A Cell study where antibodies from long COVID patients with new onset pain caused pain-like symptoms in mice
    • Spike protein found in gut tissue, and the inflamed tissue around it in long COVID patients
    • Herpesvirus reactivation after COVID, including HHV-6 in saliva that tracked with severity
    • Mast cell activation, POTS, and why Pepcid and Claritin help some patients
    • Clinical trials underway: a spike-binding monoclonal antibody, antivirals for herpesviruses, micro Tesla magnetic therapy, low-dose rapamycin, and auricular vagus nerve stimulation
    • First steps for someone with long COVID: tilt table test, blood work, active stand test, breath work, and sodium

    Follow The Smartest Doctor In The Room wherever you get your podcasts.

    Guest Contact

    Website
    https://www.putrinolab.net/

    LinkedIn profile
    https://www.linkedin.com/in/david-putrino-bb86aa11/

    YouTube channel
    https://www.youtube.com/@CoRESinai

    Social media

    X: @putrinolab
    Instagram: @putrino_lab

    Contact Dr. Mitchell:

    Email: care@mitchellmedicalgroup.com
    Website
    Instagram
    YouTube
    Facebook
    LinkedIn


    Book: Conquering Candida
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    59 min
  • Ep. 248 - The Best Kept Secret in the field of Allergy: Food Allergies Can Be Treated

    Ep. 248 - The Best Kept Secret in the field of Allergy: Food Allergies Can Be Treated
    3 Nov 2026
    Yes, food allergies can be treated. Xolair (omalizumab) is the first FDA-approved treatment for any food allergy beyond peanut, and it can lower the risk of a severe reaction after accidental exposure for children age one and older and for adults, including people with multiple food allergies. It is not a cure, and patients still avoid their trigger foods.Dr. Dean Mitchell talks with Dr. Dale Umetsu, the allergist-immunologist who spent decades in academic medicine at Stanford and Harvard before moving to Genentech to help move Xolair toward FDA approval for food allergy. Dr. Umetsu is the author of Beyond Avoidance: A Physician's Pursuit to Transform Food Allergy Treatment.

    In this episode:
    • How Xolair compares with oral immunotherapy (OIT) and sublingual immunotherapy (SLIT)
    • How much protection it gives, why avoidance still matters, and how long protection lasts after injections stop
    • How dosing works, and why Xolair does not help eosinophilic esophagitis
    • Why food allergy treatment took so long to reach patients
    • Food allergy testing: ImmunoCap, component testing, and basophil activation testing

    Follow The Smartest Doctor In The Room wherever you get your podcasts.

    Guest Contact

    https://www.daleumetsu.com/
    https://en.wikipedia.org/wiki/Dale_T._Umetsu
    https://notablepeopleproject.org/dale_umetsu

    LinkedIn profile
    https://www.linkedin.com/in/dale-umetsu-b66731b5/

    Purchase Beyond Avoidance on Amazon here.

    Contact Dr. Mitchell:

    Email: care@mitchellmedicalgroup.com
    Website
    Instagram
    YouTube
    Facebook
    LinkedIn


    Book: Conquering Candida
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    Show more Show less
    1 hr and 1 min
  • Ep. 247 - Should You Get the COVID Booster and Flu Shot? Dr. Mitchell's Vaccine Q&A

    Ep. 247 - Should You Get the COVID Booster and Flu Shot? Dr. Mitchell's Vaccine Q&A
    27 Oct 2026
    DescriptionFor most people the risk from routine vaccines is extremely low and the benefit is very high, but a smaller group, including people with mast cell activation syndrome or a serious past reaction, may need an exemption. In this solo Q&A, immunologist and functional medicine physician Dr. Dean Mitchell explains how vaccines train the immune system, why childhood vaccines are timed the way they are, why he calls the measles vaccine a no brainer, and why he does not recommend COVID boosters. He covers common and rare vaccine reactions, how to document a reaction when an exemption is needed, and what he thinks about the flu shot, pneumococcal boosters, and the shingles vaccine. Dr. Mitchell also takes live questions on a severe reaction to a flu shot, vaccines during pregnancy, how to space a baby's vaccines, and vaccines and autism, plus MTHFR, B12, and homocysteine.Follow The Smartest Doctor In The Room on Apple Podcasts or Spotify so the next episode comes to you.

    Contact Dr. Mitchell:

    Email: care@mitchellmedicalgroup.com
    Website
    Instagram
    YouTube
    Facebook
    LinkedIn


    Book: Conquering Candida
    ImmunoLytics - code SmartestDoc, 5% off
    Apollo Neuro - code SMARTMD
    Show more Show less
    49 min
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