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The Popkin Method

The Popkin Method

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You’re not crazy. Your care is just fragmented. Most people bounce between specialists, apps, and online “biohacks” without ever getting real answers.


The Popkin Method is here to change that - with real, physician-led medicine that integrates the best of internal and functional approaches into one clear, personalized care.


Hosted by Matthew C. Popkin, M.D., a board-certified internist with surgical training and functional medicine expertise - this podcast explores how to reconnect the dots between your symptoms, labs, lifestyle, and deeper health goals.


Whether you're battling fatigue, inflammation, hormones, weight, or aging - this show delivers clinical insight, clarity, and next steps… with none of the hype.


Real medicine. Real results. Real transformation.

© 2025 The Popkin Method
Exercice et forme physique Fitness, alimentation et nutrition Hygiène et vie saine Maladie et pathologies physiques Médecine alternative et complémentaire
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    Épisodes
    • Personalized Peptides, Hormones, and Stem Cells: The Popkin Method for Regenerative Wellness
      Dec 30 2025

      Welcome to The Popkin Method, where real medicine meets real results. In this episode, Dr. Matthew C. Popkin tackles the buzz surrounding regenerative medicine; think peptides, hormone replacement therapy, stem cells, and exosomes. These cutting-edge therapies are making headlines everywhere, from social media to specialty clinics, but are they really a magic bullet for health and vitality?

      Dr. Popkin pulls back the curtain on what’s driving all this hype and offers a no-nonsense look at how these treatments work, who they’re for, and why personalization is key. Together, they explore how lifestyle, diet, and exercise still hold center stage, and how advanced therapies like peptides and stem cells fit into a comprehensive, physician-led care plan.

      If you’ve ever wondered whether you need more than just willpower and supplements, or if you’re tempted by “miracle cures” promised online, this episode is your essential guide to exploring regenerative medicine responsibly and effectively.


      Timestamps:

      00:00 "Comprehensive Functional Medicine Approach"

      05:57 Peptides for Healing and Repair

      08:48 "BDNF Peptides for Symptom Relief"

      12:13 Hormonal Feedback Loop Explained

      14:56 "Boosting Hormones Naturally"

      17:51 "Hormone Imbalance and Natural Remedies"

      21:31 Stem Cells & Exosomes Therapy

      25:06 Comprehensive Care Through Functional Medicine

      30:25 Optimizing Health for Weight Loss

      32:27 Beware of Counterfeit Supplements

      36:51 "Guidelines for Safe Supplement Use"

      41:57 "Ensuring Safe Stem Cell Treatments"

      45:37 "Health Essentials: Muscle, Diet, Supplements"

      46:35 Comprehensive Health and Wellness Therapies

      50:06 "The Popkin Method Overview"


      You can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.

      You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.

      Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at mcpopkinmd@yahoo.com.

      Podcast Website - https://thepopkinmethod.com/

      Matthew C. Popkin, M.D. - https://thepopkinmethod.com/about

      Podcast Partner - TopHealth - https://tophealth.care/

      “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

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      51 min
    • Breaking the Symptom Spiral: How Sleep and Stress Sabotage Your Health
      Nov 4 2025

      Welcome back to The Popkin Method, where real medicine meets real results. In this episode, Dr. Matthew C. Popkin tackles one of the most overlooked health challenges: the "wired but tired" syndrome. If you’ve been struggling with poor sleep, chronic stress, brain fog, unexplained weight gain, or low motivation, this conversation is for you.

      Dr. Matthew C. Popkin breaks down how sleep and stress create a vicious cycle that quietly wreaks havoc on your hormones, brain function, metabolism, and immune system. You'll learn why sleep is much more than just “rest”; it’s foundational to nearly every aspect of your health. Through real patient stories and science-backed insights, Dr. Matthew C. Popkin explains how the symptom spiral starts and, more importantly, how you can break free from it.

      From practical tips on improving your sleep hygiene and stress resilience, to which supplements can make a real difference (and which habits might be sabotaging your nights), this episode is packed with actionable strategies. Whether you’re searching for ways to boost your daily energy, sharpen your focus, or finally get a restful night's sleep, Dr. Matthew C. Popkin shares his proven method to help you stop the cycle and reclaim your health.

      Tune in and discover how fixing your sleep and stress can be the key to unlocking everything else and why sometimes, what you really need isn’t just another pill, but true sleep rehab.


      Timestamps:

      00:00 "Cortisol, Stress, Sleep Disruption"

      09:54 "Sleep: The Key to Health"

      15:43 Sleep: Key to Combating Burnout

      17:57 Stress Disrupts Cortisol Rhythm

      26:21 "Creatine, Sleep, and Brain Health"

      29:56 "Improving Sleep with Cortisol Insights"

      37:11 Sleep, Stress, and Hormones Analysis

      42:37 Unhealthy Habits Disrupting Sleep

      49:52 "Phone Radiation Impacts Sleep Quality"

      53:25 Sleep Improvement Without Supplements

      57:18 Mindfulness and Sleep Strategies

      01:04:56 "Restoring Body's Natural Rhythm"

      01:12:12 Sleep Aid Alternatives and Solutions

      01:13:29 Sleep and Stress: Silent Drivers


      You can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.

      You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.

      Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at mcpopkinmd@yahoo.com.

      Podcast Website - https://thepopkinmethod.com/

      Matthew C. Popkin, M.D. - https://thepopkinmethod.com/about

      Podcast Partner - TopHealth - https://tophealth.care/

      “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

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      1 h et 15 min
    • The Four Crucial Lab Tests Most Doctors Miss and Why They Matter for Your Health
      Sep 11 2025

      Welcome back to The Popkin Method, where real medicine meets real results. Have you ever left the doctor’s office feeling frustrated because your bloodwork was “normal,” but you still feel tired, foggy, or just not yourself? This episode is for you. Dr. Matthew C. Popkin reveals the four crucial labs that most physicians overlook: tests that could make all the difference between simply surviving and truly thriving. We’ll unpack why standard labs often miss the real issues, which advanced markers you should be asking for, and how understanding your unique bloodwork can unlock better energy, mental clarity, and long-term health. If you’re ready to go beyond the basics and get answers about your health that actually translate to results, you won’t want to miss this episode.


      Timestamps:

      00:00 Advanced Lipid Profiles for Heart Risk

      05:06 Advanced Lipid Profiling for Heart Health

      09:52 Gene Mutation Impacts Treatment Strategies

      12:12 "Supplements for MTHFR Gene Mutation"

      16:48 Advanced Testing for Heart and Mental Health

      18:08 Personalized Medicine Through Genetic Testing

      22:00 Navigating Medical Testing and Insurance

      27:12 "Proactive Health: Beyond Insurance Limits"

      29:04 Preventing Diabetes Through Early Intervention


      You can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.

      You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.

      Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at mcpopkinmd@yahoo.com.

      Podcast Website - https://thepopkinmethod.com/

      Matthew C. Popkin, M.D. - https://thepopkinmethod.com/about

      Podcast Partner - TopHealth - https://tophealth.care/

      “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

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      31 min
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