Systemic Lupus Erythematosus (SLE)
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Systemic Lupus Erythematosus (SLE)
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This episode is a comprehensive overview of Systemic Lupus Erythematosus (SLE), an autoimmune disease where the immune system attacks the body’s own tissues.
We detail the pathogenesis of SLE, focusing on complex immune-related mechanisms, such as the roles of the complement system, autoantibodies like anti-C1q and anti-dsDNA, and the dysfunction of Neutrophil Extracellular Traps (NETs).
We also examine how metabolic irregularities, specifically dyslipidemia and alterations in lipid and glucose metabolism within immune cells, contribute to disease development and associated complications like cardiovascular issues and lupus nephritis.
#LupusAwareness #AutoimmuneDisease #SLE #ImmuneSystem #LupusNephritis #medicalpodcast
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