What if the root cause of brain fog, chronic illness—and even autism—wasn’t just neurological… but a metabolic problem at the cellular level?

In this episode, Dr. Adam Rinde sits down with Dr. Kurt Woeller, Chief Medical Officer at Mosaic Diagnostics, to break down the critical role of mitochondria in complex chronic conditions. From fatigue and gut dysfunction to regressive autism, this conversation explores how mitochondrial dysfunction may be a hidden driver behind it all.

You’ll learn how the Organic Acids Test (OAT) provides a powerful window into metabolic health, revealing patterns that can guide targeted treatment—and why markers like succinic acid can signal deeper dysfunction.

Dr. Woeller also shares how advanced tools like the MitoSwab can uncover issues within the electron transport chain, and why healing isn’t something you can force—but something you must support.

This episode is both a deep dive into biochemistry and a grounded reminder that true healing starts with restoring balance.

• What mitochondria actually do—and why they matter more than you think
• The difference between mitochondrial dysfunction vs disease
• Early signs of mitochondrial imbalance (brain, gut, immune system)
• How the Organic Acids Test reveals hidden metabolic issues
• Why succinic acid is a key marker to watch
• The role of toxins, infections, and nutrient deficiencies
• How the MitoSwab test evaluates mitochondrial function
• Why pushing treatment too fast can backfire
• The importance of lifestyle, stress, and natural rhythms in healing

:🎯 Who This Is For

• Parents navigating autism or developmental concerns
• Practitioners in functional or integrative medicine
• Anyone struggling with fatigue, brain fog, or chronic illness
• Listeners curious about root-cause health and advanced testing

🔗 Connect with Dr. Kurt Woeller:

• Integrative Medicine Academy
• Functional Medicine Doc Talk Podcast
• Substack: drwoeller.substack.com

If you found this episode helpful, share it with someone who needs a new perspective on healing.

Most skincare advice is focused on fixing what you can see—wrinkles, texture, tone. But by the time those changes appear, the underlying biology has already been shifting for years.

In this episode of The One Thing Podcast, Dr. Rinde sits down with pharmacist and founder of Atika Wellness , Lily Shapiro, PharmD – to explore a more accurate way to think about skin health—one that moves beyond “anti-aging” and toward what she calls skin span.

Lily breaks down the science behind how skin actually ages and why many popular solutions fall short. From the truth about collagen and biotin to the limitations of topical products, this conversation challenges some of the most common assumptions in the skincare world.

You’ll also learn the four core drivers of skin longevity—collagen integrity, antioxidant balance, lipid barrier function, and mitochondrial health—and how a systems-based approach can support your skin from the inside out.

If you’re looking for a clearer, more science-backed way to approach your skin and your health, this episode will give you a new framework to work from.

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Topics covered:
• Why “anti-aging” is the wrong framework
• The truth about collagen, biotin, and hyaluronic acid
• The CALM framework for skin longevity
• How hormones impact skin, especially in midlife
• Why most supplements fall short
• The connection between internal health and visible skin changes

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Follow Dr. Rinde for more conversations focused on the one thing that truly moves your health forward.

Show links: https://www.atikawellness.com/

About our guest:

About Lily Shapiro, PharmD

Lily Shapiro is a pharmacist and the founder of ATIKA, a nutritional dermatology brand built on scientific clarity, therapeutic dosing, and a commitment to skin longevity. Her work centers on helping women nourish the biological foundations of resilient, healthy skin through evidence-based daily nutrition.

During her 40s, Lily began noticing the early signs of collagen decline, dryness, and barrier changes that accompany midlife transitions. What she found in the supplement aisle were under-dosed blends, fragmented routines, and marketing-driven formulations that lacked clinical integrity.

As a pharmacist trained in pharmacology, nutrient metabolism, and compounding, she saw an opportunity to bring therapeutic precision into the ingestible beauty space. ATIKA was created to offer one clinically aligned, properly dosed formula supporting the four core pillars of skin health: collagen structure, lipid barrier integrity, antioxidant defense, and cellular renewal.

• Evidence before trend. Every ingredient is selected based on published human data, not aesthetics or hype.
• Therapeutic dosing. Clinical outcomes require clinical amounts — not pixie-dust blends or proprietary dilution.
• Mechanism-first formulation. Collagen synthesis, barrier lipids, oxidative stress, and cellular energy work together; the formula must reflect that integration.
• Restraint and transparency. No exaggeration, no over-claiming, no clutter — only what is necessary and clinically relevant.

• Doctor of Pharmacy (PharmD)
• Clinical background in compounding and women's health
• Experience analyzing ingredient pharmacokinetics, nutrient pathways, and therapeutic dosing
• Founder & Formulator of ATIKA Advanced Skin Nutrition

Her work reflects a belief that skin longevity begins with foundational biology — collagen structure, barrier lipids, detoxification of oxidative stress, and cellular energy. ATIKA exists to bring these truths to the center of daily ritual.

Why Some Patients Do Everything Right — and Still Don’t Fully Heal

Some patients do everything right — and still don’t fully heal.

They follow the plan. Change their diet. Take the supplements. Commit to lifestyle shifts. Show up consistently. And yet something deeper remains unresolved.

After more than twenty years in clinical practice, Dr. Adam Rinde has seen this pattern repeatedly. At some point, the question shifts from “What are we missing physically?” to “Is there another layer of healing we’re not addressing?”

In this episode of The One Thing Podcast, Dr. Rinde sits down with Eva Müller , an energy practitioner who works in the realm of emotional clearing and consciousness-based healing. Eva believes that unresolved emotional patterns, stored trauma, accumulated stress, and even ancestral influences may contribute to chronic illness in ways we don’t always measure — but still experience.

This conversation is not anti-medicine.

It’s an exploration of whether physical and energetic healing can work in parallel.

• Why some patients hit a healing plateau
• Emotional trauma and stored stress in the body
• The concept of energetic root causes
• Surrender vs. striving in chronic illness
• Why groundedness matters in spiritual work
• How energy-based practices can complement conventional care

Eva Müller is an energy practitioner and meditation guide who works with high-vibrational energetic transmissions to support emotional clearing and expanded awareness. After leaving a traditional career path that felt misaligned, she underwent years of personal transformation that led her into energy-based healing work. Today, she offers live group meditations, small-group healing sessions, and an online platform designed to support deeper emotional and energetic shifts.

Website & Offerings: https://em-healing.com
Free Weekly Live Meditation (Thursdays)

Pulsetto Vagus Nerve Device
https://pulsetto.tech
Listen for special discount mentioned in the episode

If you’ve felt like something deeper needs to shift in your healing journey, this episode may expand your framework.

Subscribe to The One Thing Podcast for conversations at the intersection of medicine, resilience, and deeper healing.