What do you learn after building companies across five generations, and investing in thousands more?
David S. Rose has been early to nearly every wave: PCs, the internet, mobile, and now AI. As the founder of Gust, he didn’t just invest in startups, he built the infrastructure that powers how startups raise money globally.
He’s a serial entrepreneur, one of the most active angel investors in the world, founder of New York Angels, and the architect behind Gust, which now supports over 2 million founders and most major angel networks worldwide.
In Today's Episode We Discuss:
00:01 – Intro & David S. Rose background
00:24 – Early entrepreneurial beginnings
02:30 – College ventures & first hustles
03:30 – First job with Senator Moynihan
04:40 – Real estate career & early tech adoption
05:20 – Inventing proptech
06:50 – First startup experiences
08:00 – WristMac and early wearable tech
10:30 – Mobile messaging startup
13:30 – Accidental Series A raise
16:00 – Wireless software & early telecom
17:30 – Internet disruption
18:00 – AirMedia & wireless internet vision
22:00 – Dot-com boom & expansion
23:40 – Dot-com crash & shutdown
24:40 – Transition to angel investing
25:30 – Founding New York Angels
26:30 – Building Gust platform
29:00 – Gust Launch & company formation
30:00 – Writing books & Quora
33:00 – AI impact on startups
35:00 – USREM & real estate marketplace
37:00 – Current ventures & roles
39:00 – Singularity University origins
42:00 – Exponential technology & Ray Kurzweil
49:00 – AI, AGI, and future predictions
52:00 – Impact of AI on venture capital
54:00 – Future of work & unemployment thesis
58:00 – UBI and economic restructuring
01:00:00 – Abundance & societal shifts
01:01:30 – Entrepreneurship in AI era
01:03:30 – Healthcare, robotics, and tech progress
01:05:00 – Founder mindset & entrepreneurship
01:07:30 – Startup success traits
01:09:30 – Investment decision framework
01:11:30 – Closing thoughts & where to find David
Along the way, he shares lessons from decades of building through booms, crashes, and paradigm shifts—and why today’s founders are playing a completely different game.
“If a machine can do your job better, faster, and cheaper… by definition, that job disappears.”
“Entrepreneurs are like cockroaches. You can’t kill us.”
From selling firewood on his first day of college to powering global startup ecosystems, David’s story is a reminder: the tools change, the stakes get higher, but the mindset that builds companies stays constant.
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