My guest today is Len Arcuri. Len is a devoted father turned passionate advocate who shares his transformative journey with raw honesty and profound insight. From the shock of his son's moderate-to-severe autism diagnosis and severe health challenges to witnessing remarkable progress through personal growth, root-cause exploration, and unconventional approaches like homeopathy, Len illustrates how a parent's internal shift can unlock a child's potential. With unwavering compassion, he empowers families to lighten self-imposed burdens, embrace informed intuition, reject limiting labels, and prioritize their own empowerment as the greatest intervention—turning a once-overwhelming path into one of deeper connection, resilience, and hope.

Autism Parenting Secret Website (Amazing !) https://autismparentingsecrets.com

Episodes https://autismparentingsecrets.com/podcast/

Elevate How You Navigate https://elevatehowyounavigate.com

email: hello@allinparent.com

0:00 The essence of Autism Parenting Secrets podcast & Len's work

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05:56 Len Arcuri & his family's journey into Autism

06:28 Regression & Diagnosis Regression noticed around 13 months; diagnosed moderate-to-severe Autism at 18 months

07:15 Son's Dramatic Progress From thought nonverbal forever to highly verbal and joyful; credits massive parenting shift and acceptance

09:39 Self-Generated Weight & Mindset Most emotional heaviness self-created (worry/frustration); growth mindset key; embrace mistakes

13:41 Pivotal Shift Moment "No one is coming"; parent must lead decisions; reject victim mentality and negative self-talk

14:14 Early Influences & Intuition "Do what it takes" attitude; rejected conventional playbook; prioritized maternal intuition

21:50 Speech Tied to Physical Health & delay linked to severe GI issues and life-threatening allergies; homeopathy sparked rapid turnaround

27:45 Navigating the school years

36:20 Podcast Origin & Purpose

41:10 EMF as Stressors & simple fixes help

46:38 EMF Science & oxidative stress; children more vulnerable

58:03 Root Causes Overview Candidates: EMFs, chemicals, glyphosate, vaccines, Tylenol; focus on child's unique factors

01:07:21 Role with Dr. Bogner

01:11:14 Transition to Coaching & helping parents transform into confident decision-makers

01:26:35 View on Autism Label

01:33:54 Contact & 2026 Vision Coaching: elevatehowyounavigate.com; Podcast: autismparentingsecrets.com; 2026 = year of empowered parents avoiding unnecessary suffering

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YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA

email: info.fromthespectrum@gmail.com

Starting with von Békésy’s traveling wave and the cochlea’s +80 mV biological battery, we move millisecond-by-millisecond through the auditory brainstem response (ABR Waves I–V), auditory nerve, cochlear nucleus, superior olivary complex, inferior colliculus, thalamic reticular nucleus, and finally primary auditory cortex (A1). The Endocochlear Potential (EP) is the highest DC voltage in the human body. As signals travel, excitation-inhibition attempts to balance that. When intact, brains can filter noise and locate meaningful sound. In Autism, reduced GABAergic sculpting (parvalbumin, somatostatin, and VIP interneuron dysfunction) plus lower myelination and a delayed Wave V — already detectable on the newborn hearing screen — turn ordinary environments into an unfiltered flood. The result is listening dissonance: a moment-to-moment perceptual struggle that collapses 40-Hz gamma, recruits massive frontal effort and emotional regions of the brain, frequently ends in sensory overload, shutdown, or literal pain. We close with the exact equation the pathway reveals: Low Inhibition + High Excitation = Sensory Overload.

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0:00 Chroma Light Devices and Daylight Computer Company

01:56 Audition & Autism; von Békésy Traveling Wave & Tonotopy; Hair Cells & Cochlear Amplifier

04:20 Endocochlear Potential (+80 mV Battery); Bioelectric Currents

06:30 Stria Vascularis, Melanin, & Water Role

08:15 Auditory Nerve – ABR Wave I (1.6 ms)

08:36 ABR Wave II (2.7 ms)09:00 Cochlear Nucleus & Early E:I

12:10 ABR Wave III – Superior Olivary Complex (3.8 ms)

12:13 Binaural Processing & Calyx of Held

15:00 ABR Wave V – Inferior Colliculus (5.6 ms)

15:42 Inferior Colliculus Gamma & Cell Types

18:00 Thalamus MGN & TRN Noise-Canceling

21:30 2021 Newborn ABR Study – Prolonged Wave V Biomarker

24:30 Listening Dissonance Explained

28:30 Auditory Cortex Gamma Collapse in Autism

32:30 Primary Auditory Cortex A1 Mini-Columns

36:00 Parvalbumin, Somatostatin & VIP Interneurons

39:00 Formula: Low GABA + High Excitation = Overload & Pain

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email: info.fromthespectrum@gmail.com

Dr. Sabine Hazan is a pioneering gastroenterologist and the first physician to launch a private microbiome testing lab in the U.S. In this powerful episode, she reveals how decades of clinical experience and cutting-edge research have convinced her that the gut microbiome—especially the near-extinction of key bacteria like Bifidobacteria—lies at the root of Autism, Alzheimer’s, cancer, and many chronic diseases. Speaking candidly about the erosion of the doctor-patient relationship, relentless censorship, and the profit-driven forces that have turned medicine into a pill-pushing machine, Dr. Hazan explains why she believes the art of medicine is dying—and how restoring the microbiome could bring it back to life

Progenabiome: https://progenabiome.com

Clinical Trials: https://progenabiome.com/clinical-trials

X: https://x.com/SabinehazanMD

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0:00 Chroma, use "BFCM2025"; Daylight Computer & Fig Tree Golf, use "autism"

2:00 Dr. Sabine Hazan; Gastroenterologist; Microbiome; Fecal Transplant; Covid, Alzheimers, Cancer, Gut Conditions

7:12 The Impact of COVID on Medical Perspectives; Censorship & Narratives

12:26 The Art of Medicine & Relationships- more than just pills (Big Harma)

16:28 Understanding Autism & Microbiome connections; Cancer

21:16 Challenges with Clinical Trials & Funding

26:58 Innovations in Treatment versus the Status Quo

31:44 Censorship & Narrative Control (Profits over Humanity); Dr. Andy Wakefield & Autism

35:52 The Role of Vaccines & Antibiotics

40:16 Future of Microbiome Research & Treatment; Bifidobacteria

47:52 Preserving the Microbiome; Mother's & Autism; Autism Research

54:18 Fighting Censorship in Science; Narrative Control

1:00:56 Lab Testing for Autism; Red Light; Dr. Jack Kruse

1:09:14 Collaborating versus Censorship

1:13:03 Humanity & Health; Profits over Humanity

1:17:27 The Medical Oath; Urgency in Microbiome & Bifidobacteria

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email: info.fromthespectrum@gmail.com

This episode dives deep into excitatory neurons—the brain’s primary “go” signal—and their outsized role in the Autistic phenotype. We explore how pyramidal neurons, powered by glutamate through AMPA and NMDA receptors, drive lightning-fast information transmission, synaptic hyperplasticity via BDNF, and elevated gamma oscillations (30–80 Hz) in V1, S1, and A1. This overactive excitatory push, paired with reduced parvalbumin and somatostatin inhibition, creates the well-documented E:I imbalance that fuels sensory hypersensitivity, one-trial learning, rigid memory encoding, repetitive behaviors, and the classic distal-connection timing mismatch from early sensory cortices to prefrontal regions.

The Autistic brain gets to the first two stops blazingly fast yet struggles to reach the final destination typical brains arrive at effortlessly.

Inhibition Episodes: https://youtu.be/cjwbog7Rk4c?si=uSaLLNmS5EJLa_iH

https://youtu.be/Oee4L7Vsj4E?si=Y5F2eVudCLhkxNw1

https://youtu.be/PBHVssvoQkM?si=A6SPedQi-Dt-DVO_

E/I https://youtu.be/ETChjRQ0SzQ?si=yIFNovzldwSZRMeT

https://youtu.be/jl0xwjnyXII?si=dmk49CMQo3Uf17ax

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00:00 Excitatory Neurons, Push-Pull System, Parvalbumin Deficiency

03:30 E:I Imbalance, Sensory Hypersensitivity, Repetitive Behaviors

07:00 Pyramidal Neurons, Glutamate, AMPA/NMDA Receptors

10:30 Brain Regions: DLPFC, Anterior Insula, V1 S1 A1

14:00 Amygdala Misnomer, Low Road vs High Road, Emotional Hub

18:30 Receptors: AMPA 1-5ms, NMDA 10-200ms, mGluR Modulatory

22:00 Gamma Oscillations, BDNF Hyperplasticity, Sensory Overload

25:30 Distal Connections, Point-A-to-Point-B Timing Mismatch

29:00 BDNF Critical Period, One-Trial Learning, Rigid Memory

32:30 TRN Dysfunction, Repetitive Behaviors, Corticostriatal Circuit

34:30 Go-Signal vs Stop-Signal, Push-Pull Bowling Bumpers

36:00 Rubenstein & Merzenich 2003, E:I Imbalance Foundation

37:08 Daylight Computer Company, use "autism" for $50 discount

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42:35 Reviews/Ratings & Contact Info

X: https://x.com/rps47586

YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA

email: info.fromthespectrum@gmail.com

Today's episode examines the thalamic reticular nucleus (TRN), a GABAergic structure that filters sensory inputs to the thalamus, influencing sensory processing and attention in Autism. We'll explore how TRN dysfunction contributes to sensory hypersensitivity, repetitive behaviors, and cognitive strengths like visual thinking. We cover the TRN’s visual, somatosensory, auditory, and limbic sectors, using vivid analogies like a security guard and staring contest to illustrate its role. These mechanisms are linked to the Autistic phenotype’s challenges and unique perceptual abilities.

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00:00 Thalamic reticular nucleus (TRN), GABAergic neurons, sensory gating

03:42 TRN functional roles, sensory gating, attentional modulation, brainwave generation, neuro-overload prevention

07:44 TRN inputs, basal ganglia, repetitive behaviors

11:15 Cognitive flexibility, prefrontal cortex, dorsal striatum, rigid responses, Autistic rigidity

14:38 TRN outputs, feedback inhibition, excitatory neurons, sensory tuning, gamma oscillations

18:35 Burst firing, tonic firing, sensory suppression, attention regulation, sleep spindles

22:12 Visual sector, "staring contest" analogy, parvalbumin & VIP interneurons, lateral geniculate nucleus, visual gating

25:50 Somatosensory sector, ventral basal complex, tactile hypersensitivity, sensory-emotional integration

29:15 Auditory sector, medial geniculate nucleus, auditory sensitivity, social processing deficits, clusters of noises in the environment, Beatles song comparison

33:00 Limbic sector, mediodorsal nucleus, anterior insula, emotional regulation, OCD-like behaviors, Leading the way in Adaptive Responses

36:47 TRN security guard analogy, sensory control, thoughts and plans, high-intensity stimuli

40:20 Visual attention, high gamma activity, subtle environmental cues, Autistic cognitive strengths

41:06 Daylight Computer Company, use "autism" for $50 discount

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email: info.fromthespectrum@gmail.com

Today's episode explores the role of inhibitory neurons & the Sonic Hedgehog (SHH) gene in shaping the Autistic phenotype, focusing on the excitation-inhibition imbalance that drives sensory hypersensitivity and cognitive challenges. Through a neuroscience lens, the episode connects these mechanisms to heightened gamma activity.

Ben Ari Episode https://youtu.be/jo-ffwF9u0Y

Parvalbumin Interneurons episode https://youtu.be/PBHVssvoQkM?si=t8WYGlcHcv7WiE-T

Visual Thinking Part 1 https://youtu.be/XqQ8jCvWzYc?si=lffUEjGHjWj4mGOM

Neurulation Part 1 https://youtu.be/gZdg9bX3Nuw?si=xvwtlz-p1hPHI8FA

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00:00 - Autistic phenotype, excitation-inhibition imbalance, sensory hypersensitivity, cognitive deficits

03:40 - Inhibitory neurons, GABA receptors, GABA-A, GABA-B, GABA-C, tonic inhibition

07:24 - Tonic firing, burst firing, phasic firing, neural oscillations, sensory processing

08:31 - Sonic Hedgehog gene, neural development, GABAergic identity, thalamic reticular nucleus (TRN)

14:48 - Parvalbumin interneurons, fast-spiking, gamma oscillations, sensory gating, dorsolateral prefrontal cortex

18:22 - Parvalbumin dysfunction, sensory hypersensitivity, visual cortex (V1), EI imbalance, brain-derived neurotrophic factor (BDNF)

22:02 - Somatostatin interneurons, feedback inhibition, dendritic modulation, sensory adaptation, hippocampus

25:43 - Vasoactive intestinal peptide (VIP) interneurons, disinhibition, pyramidal activity, attention, social processing

29:30 - Calbindin interneurons, calretinin interneurons, dendritic inhibition, sensory processing, anterior insula

33:15 - Purkinje cells, cerebellum, motor control, cognitive timing, cell loss in autism

36:00 - Evolutionary perspective, parvalbium density, neural circuit stabilization, sensory-cognitive processing

39:25 - Gamma activity, visual processing, retina, lateral geniculate nucleus, attention to detail, autistic self

39:52 Daylight Computer Company, use "autism" for $50 discount

42:13 Chroma Light Devices, use "autism" for 10% discount

45:17 Reviews & Contact Info

X: https://x.com/rps47586

YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA

email: info.fromthespectrum@gmail.com

In this episode, Dr. Ahmad Ammous, MD, exposes the profit-driven "profit mills" of modern medicine, critiquing its reliance on pills to manage symptoms rather than address root causes. Drawing from his journey as an internal medicine physician, he challenges pharmaceutical-centric practices and delves into quantum biology’s healing potential, exploring topics like light-driven energy production through melanin’s water-splitting mechanism, cytochrome sensitivity to red and blue light in the electron transport chain, and circadian biology’s role in melatonin and cortisol regulation. Dr. Ammous offers practical solutions, such as paleo diets and sunlight exposure, to optimize health, while advocating for decentralized systems, including Bitcoin, to empower patients over profits.

Modern Medicine is Profits over Humanity

THIS IS NOT MEDICAL ADVICE

Centralized Medicine = PROFITS over HUMANITY

Dr. Ammous X https://x.com/AmmousMD

Dr. Ammous website https://ammousmd.com/?v=eb65bcceaa5f

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0:00 Dr. Ahmad Ammous, MD; Internal Medicine Medical Doctor

5:22 The Harms of Medical School

8:13 The Profit Mill in Centralized Medicine & Banks; Rockefeller Medicine & Fed Reserve; Flexnor Report; Big Harma (Pharma)

14:21 The Role of Light in Life & Health; Isolated Blue Light is the new smoking

17:09 Melanin

20:13 Melanin's Role as an Antioxidant & Detoxing

23:07 Autism & Sensitivities

26:24 Melatonin's Additional Roles

29:10 The Harms of Artificial Light on Health; POMC; Cortisol

31:18 Artificial Light at Night & Sleep; Massive Hormone Disruptor

33:21 The Electron Transport Chain & OXPHOS; Cytochromes; Biological Energy; ROS; Red Light & Cytochrome C Oxidase

38:21 The Massive Scams of Heart Prescriptions, Guidelines, Cholesterol and Statins & a leading cause of death is still Heart Disease, Heart Attacks; Big Harma

49:19 Environmental Factors & Modern Diseases

53:55 Covert Push:Pull Tactic on Humans from Medicine & Health Insurance; The Profit Mills

58:38 Autism & Lifestyle; Circadian Rhythms, Diet, & GI

59:35 Daylight Computer Company, use "autism" for $50 discount

1:03:00 Chroma Light Devices, use "autism" for 10% discount

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YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA

email: info.fromthespectrum@gmail.com

Today's episode is all about Autism and its associated communication disorders, as outlined in the DSM-5-TR, focusing on social communication disorder (SCD), childhood onset fluency disorder (stuttering), speech sound disorder, and developmental language disorder (DLD), which affect 50-70%, 4-22%, 20-30%, and up to 50% of Autistic individuals, respectively. We explore neural underpinnings, highlighting hypoactivation in brain regions and brain waves are discussed that are critical for social cognition, alongside disrupted connectivity in networks like the arcuate and superior longitudinal fasciculi. Two genes- FOXP2 and CNTNAP2 are also discussed.

Other relevant episodes:

Decoding the Brain: How Reading works in Autism and Dyslexia https://youtu.be/s1-7HZchy84?si=-r9foWP8Gmw-Wsx2

Autism and Speech & Language https://youtu.be/jhAA-UWduKg?si=TfVWi9AfbFZgv8XV

Autism and Sensory Processing part 2 https://youtu.be/iWy9Rligzic?si=2LATDK0bPl6jjat9

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00:00 - Introduction to Autism and Communication Disorders; DSM-5-TR, social communication, pragmatic deficits, stuttering, speech sound disorder, developmental language disorder

04:02 - Brain Regions and Social Cognition; medial prefrontal cortex, temporal parietal junction, superior temporal sulcus, "theory of mind", hypoactivation

06:01 - Autistic Phenotype and Neural Connectivity; Mirror neurons, sensory processing, under-connectivity, arcuate fasciculus, superior longitudinal fasciculus

11:38 - Brainwave Patterns and Measurement Techniques; EEG, MEG, gamma band, alpha band suppression, fMRI, DTI & Factional Anisotropy

16:27 - Genetic Contributions to Communication; FOXP2, CNTNAP2, neural circuits, synaptic plasticity, language processing

19:56 - Social Communication Disorder (SCD); Overview pragmatic language, non-verbal cues, autism differentiation

24:45 - Childhood Onset Fluency Disorder (Stuttering); basal ganglia, motor planning, rTMS, dopamine signaling, Go-Stop, Go-Stop, Go-Stop...

30:05 - Speech Sound Disorder Speech; Broca’s area, superior temporal gyrus, articulation errors, PROMPT therapy

35:25 - Developmental Language Disorder (DLD); Broca’s area, Wernicke’s area, language comprehension, early intervention

40:56 - Importance of Early Intervention; speech therapy, neural connectivity, personalized interventions, neurofeedback.

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email: info.fromthespectrum@gmail.com