In this episode of Longevity Unlocked, Coach Kyle and Dr. K break down the real differences between IBU (Extracorporeal Blood Oxygenation & Ozonation), plasmapheresis, and Therapeutic Plasma Exchange (TPE)—and why many plasma-based detox and longevity treatments don’t work the way they’re marketed.

They explain how plasmapheresis and TPE remove only plasma, why people are paying thousands of dollars for treatments they can legally get paid to do, and the often-overlooked fact that TPE requires IV albumin sourced from donated human blood. Kyle and Dr. K discuss what is (and isn’t) screened in donated blood products, why TPE fails to address toxins stored in red blood cells and tissue, and how influencer-driven trends have pushed these therapies into the spotlight.

The conversation then shifts to IBU, detailing how it filters whole blood, adds ozone-based hyperoxygenation, uses ultraviolet light, and removes inflammatory water and environmental toxins—all without introducing foreign blood products. Listeners walk away with a clearer understanding of which therapies actually remove toxins, which ones fall short, and how to make informed decisions before spending $5,000–$10,000 on plasma exchange treatments.

Plasmapheresis removes plasma only and discards it while returning red blood cells unchanged. People often pay thousands for plasmapheresis despite being able to donate plasma and get paid. TPE replaces discarded plasma with IV albumin sourced from donated human blood. IV albumin is not synthetic and is derived from pooled human donors. Donated blood products are not screened for every pathogen or environmental exposure. TPE removes only toxins circulating in plasma at that moment. Toxins stored in red blood cells and tissue are not addressed by TPE. IBU filters whole blood, including red blood cells and plasma. IBU operates as a closed-loop system with no donated blood products. Ozone in IBU hyperoxygenates blood and reduces inflammation. IBU removes microplastics, pesticides, glyphosate, BPA, and other environmental toxins. Waste buckets from IBU have been independently tested to confirm toxin removal. The high cost of TPE is largely driven by albumin pricing. IBU resolves many of the structural flaws of TPE. Popularity and influencer exposure do not equal better medicine.

00:00 – How IBU works: filtration, ozone, UV, reinfusion 00:40 – Show intro & medical disclaimer 01:15 – Episode overview: IBU vs TPE vs plasmapheresis 01:55 – What plasmapheresis actually is 02:35 – Paying for a treatment you can get paid to do 03:20 – Claimed benefits of plasmapheresis 03:55 – Introduction to Therapeutic Plasma Exchange (TPE) 04:20 – What replaces plasma in TPE 04:50 – Where IV albumin really comes from 05:40 – What donated blood is not screened for 06:30 – Why TPE doesn’t remove tissue-bound toxins 07:05 – Why TPE costs $5,000–$10,000 per session 07:40 – How IBU fundamentally differs from TPE 08:05 – Toxins removed through IBU 08:45 – Why whole-blood filtration matters 09:15 – Why TPE became popular 09:45 – Future blood filtration technologies 10:25 – Final comparison: IBU vs TPE 10:55 – Closing thoughts & disclaimer

The Longevity Center FL Integrative, osteopathic, and regenerative healthcare — all under one roof. Location: 580 Village Blvd #210, West Palm Beach, FL 33409 Website: https://www.thelcfl.com/ Instagram: https://www.instagram.com/thelcfl/

Produced by: Clearview Studio Filmed by: Jackson Young (@clearviewstudios)

Podcast Website: https://peakperformancepodcast.online/ Instagram: @thepeakperformancepod X (Twitter): @PeakPerformPod Dr. K on Instagram: @theosteodoc