In this episode of Biology Career Insights, we dive into groundbreaking research using the African turquoise killifish, a fast-aging vertebrate, to study kidney aging. Despite their naturally short lifespan, these tiny fish are helping scientists uncover how SGLT2 inhibitors—drugs originally developed for diabetes—can preserve kidney function, protect capillary networks, and prevent inflammatory damage as organs age.We explore why these medications provide cardiovascular and renal benefits in humans far beyond blood sugar control and how studying rapid-aging species accelerates the development of life-extending therapies.🎙️ Powered by AI, curated by scientists, and made for educational purposes only.🔔 Don’t forget to subscribe for more insights into biology careers, cutting-edge research, and the stories shaping the future of biotechnology.Timestamps (Optional):0:00 – Introduction1:20 – Why the African turquoise killifish is a unique aging model3:45 – SGLT2 inhibitors and kidney preservation6:30 – Implications for human health and longevity9:00 – Key takeaways

New research from Stanford University reveals a surprising mechanism: neurons may actively erase their own connections when triggered by amyloid beta and inflammation. In this video, we break down how two major Alzheimer’s pathways converge on a single receptor that drives synapse loss—and why this discovery could reshape future therapies.

Instead of focusing only on clearing amyloid plaques, this study suggests protecting synapses directly may be key to preserving memory.

🔬 What you’ll learn:

• How amyloid beta and inflammation interact in Alzheimer’s

• Why neurons are not just passive victims of the disease

• What synapse pruning has to do with memory loss

• How this discovery could influence next-generation Alzheimer’s drugs

🎧 This content is part of Biology Career Insights (BCI)—where we explore the science, careers, and innovations shaping the future of biotechnology.

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📌 Key Reference:
Brott et al., Proceedings of the National Academy of Sciences (PNAS), 2026
Wu Tsai Neurosciences Institute, Stanford University

What is the best time of day to exercise — morning, midday, or evening?

In this episode of Biology Career Insights (BCI), we take a biology-driven look at how exercise timing interacts with circadian rhythms, metabolism, muscle performance, sleep, and long-term health.

Drawing from peer-reviewed research and biological principles, we explore:

• Why morning workouts support consistency and mental energy

• How afternoon and evening exercise align with peak muscle performance

• What recent studies reveal about midday activity, longevity, and cardiovascular health

• How exercise timing affects sleep, oxygen efficiency, and metabolic responses

• Why consistency matters more than the clock for long-term health

This episode bridges biology, evidence, and real life, helping you decide when exercise fits best with your biology and schedule.

🎧 Subscribe to Biology Career Insights for conversations with leading voices in life sciences—plus, from time to time, a daily dose of biology explained simply and backed by science.