HOST: Hildy Grossman, CO-HOST: Jordan Rich
GUEST: Sumati Ram-Mohan, Vice President of Upstage Lung Cancer

Why did singer and cabaret performer Hildy Grossman launch Upstage Lung Cancer 18
years ago? In this episode, Hildy describes how a fluke accident resulted in early detection of
her lung cancer and put her on a life-changing path. When faced with an early diagnosis, Hildy
didn’t just ask "Why me?"—she asked, "What now?" She realized that while anyone with lungs
can get lung cancer, not everyone has a stage to fight it. Thus, Upstage Lung Cancer was created
as the only lung cancer organization to exclusively produce concerts and the performing arts to
raise awareness, reduce stigma and fund cutting edge medical research.
In a meeting of Art & Science, our guest, Sumati Ram-Mohan, a scientist and dancer, shares her
story of how and why she reached out to Hildy. Now the Vice President of Upstage Lung
Cancer, Sumati discusses how her experience in lung research and her passion for the stage help
move this organization forward. Among other things, this podcast series, now ranked in the top
5 out of 40 lung cancer podcasts, was created to be both engaging, enjoyable and
informative. They discuss almost two decades of outreach and impact, ending with a look ahead
to this year's Fall Concert – an evening of joy aimed at this difficult disease.

We thank our sponsors Lilly, Bristol Meyers Squibb, Revolution Medicines, Boehringer
Ingelheim, and Takeda for their generous support of our podcast series Backstage @ Upstage.

HOST: Hildy Grossman CO-HOST, Jordan Rich

Guests: Justin Gainor, MD, Director of Targeted Immunotherapy at the Massachusetts General Hospital and David Barbie, MD, Director of the Barbie Lab at Dana Farber Cancer Institute Targeting Innate Immunity in Cancer

Lung cancer has long been one of the most complex and difficult cancers to treat. But what if we could outsmart it—not just with surgery, chemotherapy, or radiation, but by training the immune system itself? This episode explores a revolutionary question: Could a vaccine change the future of lung cancer? To shed light on answers to this question are Dr. Justin Gainor, whose interest is in vaccine development, and Dr. David Barbie, who returns to Backstage @ Upstage to explain how the immune system responds to cancer. Our renowned guests describe the challenges of creating a therapeutic vaccine and why a preventative vaccine is less likely to succeed. They detail how the immune system’s delicate operations need to be understood to successfully develop a vaccine to treat lung cancer. Moreover, you’ll want to hear about the groundbreaking promise of “personalized vaccines” tailored to an individual’s unique genomic markers, and how these cutting-edge vaccines will change the future of oncology forever.

HOST: Hildy Grossman, CO-HOST: Jordan Rich
GUESTS: Jessica Lin, MD., Sarah Craig, Frank Marotta

Hearing the diagnosis of Stage 4 can be devastating, but today, it is no longer the final word. More people are living with Stage 4 lung cancer than ever before, thanks to a revolution in innovative treatments, immunotherapy and precision medicine.
Join us for a profoundly moving and informative episode. Sarah Craig, 31 years old with a cough and Frank Marotta, reporting to his geriatrician concerns about memory loss, share the terrifying moment they heard their diagnosis of advanced lung cancer. They graciously share their personal lung cancer journeys and where they found hope.
Renowned medical oncologist Dr. Jessica Lin answers the difficult questions: How does lung cancer metastasize, and how does a doctor compassionately deliver a life-altering diagnosis? She shares her approach to guiding patients through their darkest moments. Dr. Lin also describes how cutting-edge tools like Next-Generation Sequencing (NGS) and PD-L1 testing are now standard biomarker evaluations, fundamentally shifting care from generalized chemo to truly personalized targeted therapy and immunotherapy. Learn how this new era of evaluation and treatment is bringing tangible hope to those who need it most.