The Truth about HRT: Four Experts. Four Perspectives. What Does the Evidence Really Tell Us?

Professor Susan Davis, Professor Annice Mukherjee, Professor Aimee Spector and Dr Juliet Balfour.

For this World Menopause Day special, I am doing something a little different. HRT has become one of the most talked-about topics in women's health, yet it is also one of the most misunderstood.

Social media, headlines and personal stories can make it difficult to separate evidence from opinion, leaving many women confused about the benefits, risks and limitations of treatment.

I've invited four internationally recognised menopause experts to discuss four areas where women need clearer, evidence-based information about hormone therapy;

1/ Dr Juliet Balfour explores what we know, and don't know, about the benefits and risks of HRT.
Dr Juliet Balfour is an experienced NHS GP with a longstanding interest in women's health. She is a British Menopause Society registered menopause specialist with the Advanced Certificate in Menopause Care and a member of the BMS Medical Advisory Council. She is the Lead for the Somerset NHS Menopause Service and director of Wells Menopause Clinic, a private online clinic.

2/Susan Davis examines the evidence for testosterone, including who may benefit and who may not.
Susan Davis is a Monash University Vice- Chancellor’s Distinguished Professor and an Australian National Health and Medical Research Council L3 Investigator. She is Head of the Women’s Health Research Program, and Head of the Women’s Endocrine Clinic, the Alfred Hospital Melbourne. She has published over 500 scientific papers and is considered one of the world leaders in research into oestrogens and androgens in women. She has written two books.

3/ Annice Mukherjee discusses menopause management after breast cancer and how women can navigate treatment decisions in this complex area.
Professor Annice Mukherjee is an NHS hospital physician and endocrinologist with a medical career spanning nearly 30 years. She specialises in general medicine and endocrinology with a career long interest in complex medical illness, quality of life in endocrine disease, hormone problems in cancer survivors, including early menopause and other complex menopause issues as well as managing complex fatigue. She has supported thousands of women going through menopause to help them manage symptoms and improve their quality of life and overall health safely. She is the author of the book The Complete Guide to the Menopause.

4/Aimee Spector updates on the latest evidence of whether HRT can reduce the risk of dementia.
Professor Aimee Spector is Professor of Clinical Psychology of Ageing and Director of the University College London International Cognitive Stimulation Therapy (CST) centre and ‘Menopause Mind Lab’. Her expertise lies in the global development and evaluation of complex interventions for ageing. She was recently commissioned by the World Health Organisation to support their guidelines around Menopause Hormone Therapy and dementia risk.

From one world to another: the untold side of adoption – resilience, strength, beauty and life Ionica Adriana is an actress, presenter, broadcaster and speaker. Born in Romania in the late 1980s, she spent the first two and a half years of her life in a Romanian orphanage before being adopted by a British family and moving to Yorkshire. She has since built a successful career in television, radio and theatre, appearing in productions including The Syndicate, Coronation Street and Smoggie Queens. She has also presented for BBC Radio York, BBC Politics North and Countryfile Live. In recent years, Ionica has spoken openly about her adoption journey, including searching for and finding her birth mother, and has explored the legacy of Romania's orphanage system through documentary work such as Ceausescu's Children. Instagram: @ionica_offical_ For this special Adoption Week episode, Ionica talks about her adoption journey, from spending her early childhood in a Romanian orphanage to being adopted by a loving family in Yorkshire. Ionica describes the emotional experience of reconnecting with her birth mother and sisters as an adult, reflecting on identity, belonging and the importance of honesty in adoption. She also discusses the realities of Romania’s orphanage system, challenges common misconceptions about adoption, and highlights the life-changing difference adoption can make for children in need. Throughout the conversation, she celebrates the families who adopt, encourages openness around adoption stories, and shares her belief that compassion, connection and love can help shape a brighter future for everyone involved.

Date of episode recording: 2026-10-01
Language of episode: English
Presenter: Professor Joyce Harper
Guest: Ionica Adriana
Producer: Joyce Harper

Dr Stacey Bryan (BSc MBBS MRCOG MD) is a consultant gynaecologist and gynaecological cancer surgeon at Imperial College Healthcare NHS Trust, where she completed her subspecialty training in gynaecological cancers. She obtained her undergraduate degrees in Biomedical Science and Medicine, at St George’s University of London in 2008, and membership to the Royal College of Obstetricians and Gynaecologists in 2015. She has undertaken research into HPV and early detection of cervical cancers and was awarded a Doctor of Medicine degree from the Institute of Women’s Health at University College London (UCL) in 2022.

Her work has led to publications and presentations at both national and international conferences. Staceys practice focuses on the diagnosis and management of gynaecological issues including cancer and non-cancer. She specialises in complex benign and cancer surgery, colposcopy and acute diagnostic services, vulval/vaginal cancer, cervical cancer, ovarian cancer, endometrial cancer, rapid diagnostics, pre-invasive cervical and vulval disease. As such she is able to offer a one stop service including gynaecological ultrasound scanning. She is the lead for Vulval Cancers at Imperial College London. https://eveappeal.org.uk/

In this episode Joyce speaks with consultant gynaecological cancer surgeon Dr Stacey Bryan about two of the least talked about gynaecological cancers: vulval and vaginal cancer. Together they discuss the symptoms to look out for, including persistent itching, soreness, skin changes, bleeding and unusual discharge, as well as who is most at risk and the treatment options available. One of the most important messages from this conversation is the need to know what is normal for your body.

Stacey encourages women to check their vulva every month, be aware of any changes, and seek medical advice if they notice anything unusual. Although vulval and vaginal cancers are rare, early diagnosis can make a significant difference to outcomes. The episode also explores the links with HPV, the impact of treatment on quality of life and intimacy, and why partners can play an important role in recognising changes. This is the final episode in the gynaecological cancer mini-series and is packed with practical, potentially life-saving information that every woman should hear.

Date of episode recording: 2026-09-17
Language of episode: English
Presenter:Professor Joyce Harper
Guests: Dr Stacey Bryan
Producer: Joyce Harper