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The Saving Dose

The Saving Dose

By: John Hsu & William Pedranti
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The podcast for those building the future of healthcare. A clinician, a healthcare attorney, and a behavioral health executive on what's actually working in addiction, adherence, and the capital reshaping both.


75% of patients do not take medications as prescribed. 125,000 Americans die from it every year. $528 billion in preventable costs trace directly to a gap the healthcare system has known about for decades and never closed: what happens after the prescription is written.

The Saving Dose is a podcast about that gap, the space between the clinic visit and the outcome, between the evidence-based treatment and the patient who never receives it, between the innovation that works and the reimbursement system that decides whether anyone can afford to deliver it.

Hosted by Kendra Allen, Dr. John Hsu, and William Pedranti, the show brings together a behavioral health revenue strategist, an addiction medicine physician, and a biotech entrepreneur to go inside the clinical, operational, and commercial realities of addiction recovery, medication adherence, opioid use disorder (OUD), and behavioral health. Three different vantage points on the same broken system. Honest about what fails, specific about why, and direct about what a real fix requires.

Topics include: MOUD and MAT clinic operations, medication-assisted treatment adherence, behavioral health reimbursement, opioid use disorder treatment, payer contracting, DEA compliance, FFS-to-value-based care transitions, and the patient adherence gap in controlled substance prescribing.

The Saving Dose is for investors evaluating the addiction recovery and behavioral health infrastructure market. For clinic operators and executives running opioid treatment programs, MOUD practices, and behavioral health facilities. For clinicians in addiction medicine and pain management. For payers and administrators navigating the cost and risk of behavioral health coverage.

New episodes every two weeks. Available on Spotify, Apple Podcasts, YouTube, and wherever you listen.

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© 2026 The Saving Dose
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Episodes
  • Addiction, Stigma, and the Treatment Gap| The Saving Dose Ep. 17 Ft. Dr. Michael Genovese
    27 Oct 2026

    In this episode of The Saving Dose, Dr. John Hsu and William Pedranti are joined by Dr. Michael Genovese, a board-certified psychiatrist and attorney whose rare dual training gives him an unusually clear view of both the clinical and legal dimensions of behavioral health. As Chief Medical Officer of Behavioral Health at Access Telecare, he leads the nation’s largest acute specialty telemedicine platform, helping hospitals deliver psychiatric and addiction care where it’s needed most. He previously served as Chief Medical Officer at Acadia Healthcare, the largest standalone behavioral health provider in the United States, and brings more than two decades of hands-on experience as an addiction specialist. He is a longtime advocate for first responders and attorneys in recovery, and recently joined the boards of the National Eating Disorders Association and Banyan Treatment Centers.

    This conversation covers the clinical and legal realities that shape how addiction is treated in America and why nearly two-thirds of people who need treatment for substance use disorders never receive it. Dr. Genovese and the hosts examine how stigma distorts clinical decision-making, what the medical community still gets wrong about opioid use disorder, and why treating the whole patient, not just the disorder, is the only approach that holds.

    00:00 Introduction
    02:01 Dr. Genovese’s path from law to medicine
    05:46 Why psychiatry captured a doctor trained for cardiology
    08:23 From one patient at a time to a facility of people
    10:16 How telemedicine reaches patients no specialist could otherwise see
    12:01 How a law degree changes the way a doctor practices medicine
    16:14 What doctors still get wrong about addiction and stigma
    18:58 When stigma becomes malpractice: cases where bias caused harm
    22:41 The CDC’s 90 MME guideline and what it actually did to patients
    23:48 Telehealth for opioid use disorder: better or worse?
    26:10 Only 15 to 20 percent of OUD patients get treatment, and we know how to change that
    28:20 First responders, the FBI National Academy, and the stigma that runs deepest
    31:16 Veterans, VR treatment, and 44 deaths a day
    37:31 Is buprenorphine trading one addiction for another?
    38:41 Why psychosocial support cannot be separated from medication
    40:11 Multidisciplinary pain treatment and why it collapsed
    41:02 What it will actually take to solve the opioid crisis
    43:37 Ignorance is not an excuse: 5,000 addictionologists for 48 million people
    46:12 One legal or regulatory change to unlock mental health and addiction care

    About the Hosts

    John Hsu, MD is the Founder and CEO of iPill and a practicing anesthesiologist with 25 years in pain management and addiction medicine. He has taken multiple products through FDA approval and commercial launch.

    William Pedranti is the COO of iPill, a Georgetown Law graduate, and co-founder of PENG Life Science Ventures. He has taken a biotech company from founding through FDA approval, commercial launch, and exit.

    About the Guest

    Dr. Michael Genovese is a board-certified psychiatrist and attorney serving as Chief Medical Officer of Behavioral Health at Access Telecare, the nation’s largest acute specialty telemedicine platform. He previously served as Chief Medical Officer at Acadia Healthcare, the largest standalone behavioral health provider in the United States. With more than two decades of experience as an addiction specialist, he is a longtime advocate for first responders and attorneys in recovery. He recently joined the boards of the National Eating Disorders Association and Banyan Treatment Centers.

    Website: thesavingdose.com

    This podcast is for educational purposes only and does not constitute medical advice. Consult a qualified healthcare professional before making any treatment decisions.

    If you or someone you know is struggling with substance use disorder, contact SAMHSA’s National Helpline at 1-800-662-4357. Free, confidential, 24/7.

    #AddictionMedicine #BehavioralHealth #TheSavingDose #OpioidCrisis #SubstanceUseDisorder #Psychiatry #Telemedicine #AddictionRecovery #Stigma #OpioidUseDIsorder #MOUD #MentalHealth #FirstResponders #HealthcarePodcast #StigmaKills #BrainHealth #PublicHealth #RecoveryPodcast #AccessTelecare #PsychiatryPodcast

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    54 min
  • The Politics of Addiction | The Saving Dose Ep. 16 ft. Andrew Kessler
    20 Oct 2026

    In the sixteenth episode of The Saving Dose, Dr. John Hsu and William Pedranti are joined by Andrew D. Kessler, JD, founder and principal of Slingshot Solutions LLC, a Washington, DC behavioral health policy consulting firm with more than two decades of experience navigating Congress, the White House Office of National Drug Control Policy, SAMHSA, and NIDA on behalf of treatment providers, advocacy organizations, and professional associations.

    Andrew has written legislation and report language passed by both the House and Senate, presented before the Scientific Management Review Board, the College on Problems of Drug Dependence, and the National Conference on Addictive Disorders, and is a frequent contributor to Politico, The Hill, and Alcohol and Drug Abuse Weekly. He is one of the few people in this space who understands both what advocates need and why Capitol Hill consistently fails to deliver it, and he says so plainly.

    00:00 Introduction
    02:34 Andrew’s path from Capitol Hill intern to DC policy specialist
    07:53 Why Slingshot Solutions has nothing to do with David and Goliath
    10:02 The fourth decade of the opioid epidemic and the gap between suffering and policy
    11:06 Why stigma is still the number one obstacle on Capitol Hill
    13:00 Addiction as a brain disease: what society still does not understand
    14:25 How Hollywood shapes what policymakers think treatment looks like
    17:44 The $4 trillion problem and why 85% of people with OUD never get treatment
    24:20 The three-legged stool: prevention, treatment, and recovery
    26:07 Reducing overdose deaths by more than 50% is possible, so why aren’t we
    29:38 The workforce crisis: retention, not recruitment, is the problem
    31:53 Why Medicaid reimbursement for SUD has never recovered from the 1960s
    35:40 The $57 billion opioid litigation settlement and what actually happened to it
    43:12 If the president gave you one year and full backing: Andrew’s three moves
    51:47 Homelessness, addiction, and what the current administration is actually saying
    54:38 Robert F. Kennedy Jr., 14 years of heroin addiction, and zero days homeless
    57:56 A vision without funding is a hallucination: how Andrew holds the White House accountable
    1:00:46 What Slingshot Solutions does and how to reach Andrew

    About the Hosts

    John Hsu, MD is the Founder and CEO of iPill and a practicing anesthesiologist with 25 years in pain management and addiction medicine. He has taken multiple products through FDA approval and commercial launch.

    William Pedranti is the COO of iPill, a Georgetown Law graduate, and co-founder of PENG Life Science Ventures. He has taken a biotech company from founding through FDA approval, commercial launch, and exit.

    About the Guest

    Andrew D. Kessler, JD is the founder and principal of Slingshot Solutions LLC, a Washington, DC consulting firm specializing in behavioral health policy. With more than 20 years of experience in substance use disorder policy, he has written legislation and report language passed by both the House and Senate, collaborated with congressional offices, the White House ONDCP, NIDA, and SAMHSA, and represented organizations including the International Certification and Reciprocity Consortium, the California Consortium of Addiction Programs and Professionals, and Faces and Voices of Recovery. He is a frequent contributor to Politico, The Hill, and Alcohol and Drug Abuse Weekly, and speaks nationally on substance use policy and advocacy. He speaks in a personal capacity.

    Website: thesavingdose.com

    This podcast is for educational purposes only and does not constitute medical advice. Consult a qualified healthcare professional before making any treatment decisions.

    If you or someone you know is struggling with substance use disorder, contact SAMHSA’s National Helpline at 1-800-662-4357. Free, confidential, 24/7.

    #OpioidPolicy #AddictionRecovery #BehavioralHealth #TheSavingDose #DrugPolicy #SubstanceUseDisorder #ONDCP #SAMHSA #NIDA #OpioidCrisis #HarmReduction #MOUD #MedicaidPolicy #AddictionMedicine #PublicHealth #RecoveryPodcast #StigmaKills #HealthcarePodcast #SlinghotSolutions #OpioidSettlement

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    1 hr and 6 min
  • Inside Hospital Drug Diversion | The Saving Dose Ep. 15 ft. Terry Vidals
    13 Oct 2026

    Terri Vidals has spent more than 35 years in pharmacy, with the last 15 focused on a problem most healthcare institutions prefer not to discuss: drug diversion by their own staff. She founded RExpert Solutions to help hospitals assess where their diversion vulnerabilities actually are and build programs that close them. She hosts the Drug Diversion Insights Podcast. She knows what the automated dispensing machines catch, what they miss, and what happens to patients when a clinician replaces fentanyl with saline.

    In this conversation with Dr. John Hsu and William Pedranti, Terri walks through the mechanics of diversion at the point of care, the accountability frameworks that protect patients without destroying careers, and why the home monitoring environment remains a blind spot no current system addresses.

    Chapters:
    [[00:00]] Introduction and Terri’s background
    [[10:46]] What happens when the vial has been tampered
    [[15:41]] The home monitoring black hole: no visibility after the cabinet
    [[19:00]] Diversion rates among healthcare professionals: 10 to 20 percent
    [[25:00]] Accountability vs. compassion: remove from bedside, investigate fully
    [[32:00]] The false accusation: when reporting gets used as a weapon
    [[38:00]] MOUD access and the 75% who cannot get medication
    [[43:44]] What Terri would mandate at every hospital in the country
    [[49:11]] Closing

    Connect with Terri Vidals:
    LinkedIn: https://www.linkedin.com/in/terri-vidals

    About The Saving Dose:
    The Saving Dose is a podcast about what it actually takes to close the gap between the medication adherence crisis and the patients who need care. Hosted by Dr. John Hsu, an anesthesiologist and pain management physician with 25 years of experience, and William Pedranti, a healthcare attorney and biotech operator who has taken companies from founding through FDA approval and commercial exit.

    New episodes every Tuesday. Subscribe on Spotify, Apple Podcasts, and YouTube.

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    51 min
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