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Discussions of artificial intelligence and ChatGPT are everywhere. How will this technology affect epilepsy research and care? What are the dangers and pitfalls, and what do we need to know when designing research studies that use AI technology?

Dr. Alina Ivaniuk interviewed Dr. Christian Bosselmann, an epilepsy precision medicine research fellow at the Cleveland Clinic, about the history of chatbots, the promise and pitfalls of artificial intelligence, and tips for critically evaluating studies that utilize AI.

Mentioned in the discussion:
Are AI language models such as ChatGPT ready to improve the care of individuals with epilepsy?

Comparing physician and artificial intelligence chatbot responses to patient questions posted to a public social media forum

This episode was reported by Alina Ivaniuk, and edited and produced by Nancy Volkers.

Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.

Let us know how we're doing: info@ilae.org

The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, Instagram, and LinkedIn.

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Katja Kobow is the most recent winner of the Michael Prize, an international award in epilepsy research. Her work focuses on epigenetics and epilepsy, a field that has grown exponentially in only the past 10 to 15 years. Dr. Kobow talked about her research and its potential for epilepsy diagnosis and treatment.

Epigenetics is the bookmarking system or the data management system of our genome. It decides which part of the genome is read, and when to read it. The epigenome is what makes the genome versatile in terms of regulating gene expression.

Epigenetics is crucial for all aspects of brain development and function. It’s also reversible, which has exciting implications for anti-epileptogenic therapies.

Dr. Kobow is assistant professor at the Institute of Neuropathology at the University Hospital Erlangen, Germany.

Selected recent publications:

DNA methylation-based classification of malformations of cortical development in the human brain (Acta Neuropathologica, 2022)

Molecular diagnostics in drug-resistant focal epilepsy define new disease entities (Brain Pathology, 2021)

Epigenetics explained: a topic “primer” for the epilepsy community by the ILAE Genetics/Epigenetics Task Force (Epileptic Disorders, 2020)

Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.

Let us know how we're doing: info@ilae.org

The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, Instagram, and LinkedIn.

Send comments and feedback

Are people who have their first seizure during sleep at greater or lesser risk for future seizures, compared with people who have their first seizure when they're awake? Dr. Laurent Sheybani interviews Dr. Elaine Pang, author of a 2023 paper in Epilepsia that analyzed data from 1,312 adults visiting a first-seizure clinic.

This episode also discusses a 2015 evidence-based guideline on managing a first unprovoked seizure in adults. The guideline was developed by the American Academy of Neurology and the American Epilepsy Society.

Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.

Let us know how we're doing: info@ilae.org

The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, Instagram, and LinkedIn.