Épisodes

  • Taking Ownership of Your Care After Breast Cancer Treatment | Kia Lee, Author of Lighthouse
    Oct 21 2026

    The end of active treatment is often treated as a finish line. For many patients, it is the start of a harder adjustment.


    Kia Lee was 38 when she found a lump in her right breast at the gym. She was diagnosed with stage 3 ER-positive, HER2-negative breast cancer in 2023, and over the next 20 months she went through chemotherapy, a unilateral mastectomy, proton radiation, and reconstruction. Getting proton radiation covered took a five-month fight with her insurer.


    Kia, a breast cancer recovery coach and author of Lighthouse: The Path Through Cancer, joins host Samira Daswani to talk about what happened after treatment ended. She explains why emotions she could not process during treatment surfaced once it was over, how the experience changed the way she spends her time and energy, and how body image and intimacy shift after a mastectomy and reconstruction.


    The conversation closes with practical guidance for patients approaching the end of treatment: setting aside time to reconnect with yourself, including ways to do that at home and without spending money; finding a therapist, mentor, or peers with lived experience; and asking questions until you understand the trade-offs of each decision, from hormone therapy to fertility preservation.


    Kia's views on her own treatment choices, including hormone therapy and new treatment options, reflect her personal experience. Talk with your care team about the options that are right for you.


    0:00 What have I done with 38 years?

    0:17 Introducing Kia Lee

    0:50 Finding a lump at 38: a stage 3 ER-positive, HER2-negative diagnosis

    2:13 Chemotherapy, an allergic reaction, and an insurance requirement

    2:52 Mastectomy and a five-month fight to cover proton radiation

    3:54 A six-month plan that took nearly two years

    4:29 Done with treatment, and finding the middle ground

    5:41 Hormone therapy and side effects

    6:36 Why the end of treatment was the hardest chapter

    8:40 Now what? Questioning identity and purpose

    10:14 Why emotions surface after active treatment ends

    11:56 Is processing ever finished?

    13:52 Before and after cancer: from people pleasing to boundaries

    16:33 Facing your own mortality

    18:10 Body image, reconstruction, and intimacy

    19:51 Being done and weighing new treatment options

    21:56 Advice for patients nearing the end of treatment

    24:28 Taking ownership of your treatment decisions

    25:49 How do you reconnect with yourself?

    27:52 Reconnecting without travel or spending money

    30:50 Take your time and ask the questions

    32:54 A Friday-to-Monday decision on fertility preservation

    34:21 Closing thoughts


    Kia Lee is a stage 3 breast cancer survivor, author, speaker, and patient advocate dedicated to helping people navigate life during and after breast cancer. She is the author of Lighthouse: The Path Through Cancer and Lighthouse: Surviving Narcissistic Abuse, and works one-on-one with women navigating life after breast cancer. She also facilitates a virtual support group for Breastcancer.org. Her work has been featured by Katie Couric Media, Living Beyond Breast Cancer, and Wildfire Magazine, and she has appeared on several breast cancer and survivorship podcasts.


    Website: https://kia-lee.com

    Instagram: @LighthouseSurvivor


    Patient From Hell is hosted by Samira Daswani, cancer survivor, entrepreneur, and founder of Manta Cares. Through candid conversations with patients, physicians, researchers, and healthcare leaders, the show explores the realities of cancer care while empowering patients with practical, evidence-based information.

    Connect with Patient From Hell

    Website: https://www.mantacares.com


    Disclaimer

    This podcast is intended for educational and informational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional regarding diagnosis, treatment, or medical decisions.

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    36 min
  • First-Line Treatment for Metastatic TNBC: Inside the ASCENT-03 Trial | Dr. Alissa Huston, University of Rochester
    Oct 7 2026

    This episode is sponsored by Gilead Sciences. Gilead had no involvement or input in the podcast content. Gilead is working to transform how cancer is treated. We are innovating with next-generation therapies, combinations, and technologies to deliver improved outcomes for people with cancer. From antibody drug conjugates and small molecules to cell therapy-based approaches, our portfolio and pipeline assets are creating new possibilities for people with cancer.


    UPDATE SINCE RECORDING JANUARY 2026. Since this recorded conversation, the FDA has acted on the data discussed in this episode. On May 22, 2026, Datopotamab Deruxtecan was approved for first-line metastatic TNBC in patients who are not candidates for immunotherapy. On June 24, 2026, Sacituzumab Govitecan was approved for first-line use both as a single agent and in combination with pembrolizumab for PD-L1-positive disease (CPS ≥10). Consult with your care team for the most recent indications and availability of these treatment options.


    Metastatic triple-negative breast cancer has historically had the fewest targeted options of any breast cancer subtype. The ASCENT-03 trial changed the first-line picture.


    ASCENT-03 (NCT05382299) was a phase 3, open-label, randomized trial of 558 patients with unresectable locally advanced or metastatic triple-negative breast cancer who had not received prior systemic therapy for advanced disease and who were not candidates for PD-1 or PD-L1 inhibitor therapy. Participants were randomized 1:1 to sacituzumab govitecan-hziy or to physician's choice of chemotherapy (nab-paclitaxel, paclitaxel, or gemcitabine plus carboplatin).


    0:00 Treating cancer like a game of chess

    0:44 Introducing Dr. Alissa Huston

    1:11 Breast oncology and integrative oncology in one practice

    2:58 Twenty years of change: from tumor size to molecular profiling

    4:28 Where metastatic triple-negative breast cancer stands today

    5:55 What is PD-L1, and how does immunotherapy work?

    6:46 Why immune-related side effects behave differently

    8:05 Choosing between immunotherapy, ADCs, and chemotherapy

    9:58 Inside ASCENT-03: what the trial studied and who it enrolled

    12:15 Progression-free survival, explained in plain language

    16:50 What the first appointment actually looks like

    19:22 Holding hope and toxicity in the same conversation

    20:34 Supportive and integrative tools for managing side effects

    21:29 Neutropenia, infection risk, and growth factor support

    22:50 Cumulative toxicity versus emerging toxicity

    25:47 Toxicity grading and why doses get reduced

    26:34 Why patients hide side effects, and why dose reductions are planned

    30:02 The chess analogy, revisited

    32:09 One piece of advice at diagnosis

    33:43 Rapid fire: ASCENT-03, progression-free survival, overall survival

    36:15 Rapid fire: antibody-drug conjugates and first-line treatment 37:33 What is integrative oncology?

    38:09 Closing thoughts


    Alissa Huston, MD is a Professor of Medicine and breast medical oncologist at the Wilmot Cancer Institute at the University of Rochester, and Co-Medical Director of the Pluta Integrative Oncology and Wellness Center. She earned her medical degree at the University of Buffalo, completed her internal medicine residency at Strong Memorial Hospital, and completed her hematology and oncology fellowship at the University of Pittsburgh. Her research focuses on the effects of breast cancer treatment on bone health and on evidence-based integrative approaches to symptom management during cancer treatment. She is a member of the American Society of Clinical Oncology and the Society for Integrative Oncology, and a co-author on the Society for Integrative Oncology and ASCO guideline for integrative management of anxiety and depression in adults with cancer.


    This podcast is intended for educational and informational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional regarding diagnosis, treatment, or medical decisions.

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    40 min
  • The Genetic Test Every Patient Should Have Before 5-FU Chemotherapy | Dr. Gabe Brooks
    Sep 30 2026

    Two of the most widely used chemotherapy drugs in the world, 5-FU and capecitabine, have been in use since the 1950s. A small share of patients carry variants in a gene called DPYD that slow their ability to break these drugs down, which means a standard dose behaves like an overdose in their body.


    A single genetic test can identify those patients before the first treatment. Europe recommended universal screening in 2020. The FDA updated the labels for both drugs in 2025, after years of pressure from families who had lost someone.In this episode of Patient From Hell, host Samira Daswani speaks with Dr. Gabe Brooks, a medical oncologist at the Dartmouth Cancer Center, about what DPD deficiency is, what severe toxicity actually looks like, how and when to get screened, what the test costs, and the exact question to ask before starting either drug.


    Guest:

    Gabriel Brooks, MD, MPH, is a medical oncologist and Associate Professor of Medicine at the Dartmouth Cancer Center and the Geisel School of Medicine. He co-directs the Cancer Population Sciences Research Program and specializes in gastrointestinal cancers, including colorectal cancer.


    Chapters

    00:00 Introduction

    00:27 What DPYD is and why it matters

    02:50 When toxicity turns fatal

    04:21 5-FU vs. capecitabine

    06:16 Which cancers use these drugs

    06:53 What the FDA changed

    08:26 Why the U.S. took five years longer than Europe

    11:27 Warning signs and time to onset

    15:28 How and when to get screened

    17:39 Germline DNA vs. tumor genomic testing

    20:16 The patient advocacy behind the change

    24:44 What to ask your oncologist

    26:43 What the test costs

    28:18 Closing thoughts


    Resources:

    Advocates for Universal DPD/DPYD Testing — test4dpd.org🎙️


    Patient From Hell is hosted by Samira Daswani, cancer survivor, entrepreneur, and founder of Manta Cares. Through candid conversations with patients, physicians, researchers, and healthcare leaders, the show explores the realities of cancer care while empowering patients with practical, evidence-based information.


    🔗 Connect with Patient From Hell

    Website: https://www.mantacares.com


    Disclaimer

    This podcast is intended for educational and informational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional regarding diagnosis, treatment, or medical decisions.

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    31 min
  • What Patient-Centered Research Looks Like, From a Nurse Who Became the Patient | Janice Cowden
    Sep 16 2026

    This episode is sponsored by Gilead Sciences. Gilead had no involvement or input in the podcast content. Gilead is working to transform how cancer is treated. We are innovating with next-generation therapies, combinations, and technologies to deliver improved outcomes for people with cancer. From antibody drug conjugates and small molecules to cell therapy-based approaches, our portfolio and pipeline assets are creating new possibilities for people with cancer.Recorded on location at the San Antonio Breast Cancer Symposium, December 2025.Metastatic triple-negative breast cancer remains the breast cancer subtype with the fewest targetable biomarkers and the shortest treatment algorithm. When a trial reports a double-digit progression-free survival in the first-line setting, it is worth understanding what that actually changes and how the trial was designed with patient outcomes at the center.This episode was recorded in December 2025, before regulatory action. On June 24, 2026, the FDA approved sacituzumab govitecan-hziy for two first-line indications in triple-negative breast cancer: as a single agent for adults with unresectable locally advanced or metastatic TNBC who are not candidates for PD-1 or PD-L1 inhibitor-based therapy supported by ASCENT-0, and in combination with pembrolizumab for adults whose tumors express PD-L1 with a CPS of 10 or greater supported by ASCENT-04. Janice's speculation in this episode about how PD-L1 status might factor into the guidelines has since been answered by the label.ASCENT-04/KEYNOTE-D19 NCT05382286 was a phase 3, open-label, randomized trial of 443 patients with previously untreated locally advanced unresectable or metastatic TNBC whose tumors expressed PD-L1 at a CPS of 10 or greater by the 22C3 assay. Participants were randomized 1:1 to sacituzumab govitecan plus pembrolizumab or to physician's choice of chemotherapy plus pembrolizumab. Patients in the control arm with centrally confirmed progression were offered crossover to sacituzumab govitecan.0:00 Live from the San Antonio Breast Cancer Symposium0:30 The METAvivor ribbon and what the pink ribbon leaves out1:35 Diagnosed in 2016 with a median overall survival of 9 to 15 months2:26 Nine years later3:20 From pediatric nursing to research advocacy4:30 What has changed since 2017, and what has not5:26 2011: when chemotherapy was the only option5:55 On not knowing a relevant clinical trial existed6:47 Why metastatic TNBC still has no maintenance therapy7:25 What first-line treatment looks like today8:25 Inside ASCENT-049:09 Progression-free survival, defined9:59 Why a double-digit PFS is notable in this subtype11:20 Why each subsequent line of treatment works for less time11:52 How many patients never reach second line12:50 The case for a stronger first-line option13:21 Crossover design, and why it matters to patients14:33 What crossover means in a randomized trial15:56 Patient advocates in clinical trial design18:59 Quality of life versus quantity of life21:48 Rapid fire: metastatic breast cancer and metastatic TNBC23:06 Rapid fire: first line, second line, progression-free survival24:00 Rapid fire: immunotherapy and antibody-drug conjugates24:59 Advice for the newly diagnosed26:04 What she wants next: a biomarker26:52 On ADCs, tolerability, and the need for novel targetsJanice Cowden, RN is a research patient advocate living with metastatic triple-negative breast cancer. She practiced as a registered nurse for approximately 22 years, primarily in pediatrics, and later worked as a pharmaceutical sales representative. She was diagnosed with stage I triple-negative breast cancer in 2011 and with metastatic disease in 2016, and completed the Living Beyond Breast Cancer advocacy training program in 2017.This podcast is intended for educational and informational purposes only and should not be considered medical advice.

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    30 min
  • Health Equity in Cancer Starts in the Lab | Dr. Eugene Manley, Jr., PhD
    Sep 2 2026

    Researchers studying lung cancer draw on more than 800 cell lines as a scientific baseline. Not one of them came from a Hispanic/Latin(x), American Indian/Alaska Native, or Native Hawaiian/Pacific Islander patient, and only about 3% are from Black patients.

    Eugene Manley Jr., PhD is a biomedical research scientist, mechanical engineer, patient advocate, and the Founder and CEO of the STEMM & Cancer Health Equity (SCHEQ) Foundation in New York City. Before founding SCHEQ, he served as Director of STEM Workforce Initiatives at LUNGevity. He also co-authored the review in Frontiers in Oncology that uncovered the patient mix and cataloged the lung cancer cell lines available to researchers worldwide.

    In this episode, he and host Samira Daswani trace a problem most conversations about clinical trial diversity never reach. The underrepresentation does not begin at enrollment. It begins upstream, in the cell lines, reference genomes, and funding decisions that shape what science gets done at all.

    Dr. Manley’s review found 390 lung cancer cell lines from Asian patients and nearly 200 from White patients, but only 31 from Black patients and none at all from three other groups. When the input material is not representative, no amount of downstream clinical trial recruitment can fix it.


    The conversation covers:

    • Why cell lines and reference genomes are the real starting point for drug development

    • What the 2023 Frontiers in Oncology review found, and what it means for who a drug is designed to work on

    • How funding decisions shape which questions researchers can even ask

    • Why patients enroll in trials at much higher rates when someone simply asks

    • What to request at diagnosis, including biomarker testing, ideally NGS, and a patient or nurse navigator

    • How to read your own chart, advocate for accuracy, and document discrepancies while you are still in the hospital

    • What Dr. Manley learned about advocating for himself while on Medicaid


    CHAPTERS

    00:00 The bias does not start at the clinical trial

    00:23 Meet Dr. Eugene Manley Jr., PhD

    01:15 Detroit roots, chronic asthma, and the road into science

    02:31 Why a bench scientist became a patient advocate

    03:26 Experiencing medical racism as a patient

    05:24 Finding your voice when the system is not listening

    07:08 "Alert and oriented": how three words shape your care

    08:10 Bring a proxy and read your chart in real time

    10:47 When the chart becomes fact: correcting your record

    11:20 Why oncology trials still are not representative

    12:46 It is not the trial, it is the whole system

    13:13 The cell line gap: what the lab starts with

    14:39 Where the bias actually begins: basic science

    15:44 Breast cancer outcomes: biology, not just zip code

    16:28 Reference genomes and databases skew European

    17:10 Why he founded the SCHEQ Foundation

    20:02 Newly diagnosed: biomarker testing and navigation

    21:19 When a clinical trial should be offered to you

    22:56 How to start the trial conversation with your team

    23:53 Inside the SCHEQ Foundation's work

    25:18 Closing thoughts


    Dr. Eugene Manley, Jr., PhD, MS, is a biomedical scientist-turned-social impact leader and Founder & CEO of the STEMM & Cancer Health Equity (SCHEQ) Foundation. With more than 20 years of experience spanning molecular biology, cancer research, nonprofit strategy, workforce development, and health equity, he has held leadership roles with organizations including AACR, LCRF, and LUNGevity Foundation. Through SCHEQ, Dr. Manley advances STEMM workforce diversity and patient-centered cancer solutions, with a focus on improving access to screening, biomarker testing, clinical trials, and survivorship resources for underserved communities.

    🔗 Connect with Patient From Hell

    Website: https://www.mantacares.com

    Disclaimer

    This podcast is intended for educational and informational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional regarding diagnosis, treatment, or medical decisions.

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    27 min
  • New First-Line Treatment: Metastatic Triple-Negative Breast Cancer with Dr. Sara Tolaney (Dana-Farber Cancer Inst.)
    Aug 19 2026

    This episode is sponsored by Gilead Sciences. Gilead had no involvement or input in the podcast content. Gilead is working to transform how cancer is treated. We are innovating with next-generation therapies, combinations, and technologies to deliver improved outcomes for people with cancer. From antibody drug conjugates and small molecules to cell therapy-based approaches, our portfolio and pipeline assets are creating new possibilities for people with cancer.


    Dr. Sara Tolaney, Chief of the Division of Breast Oncology at Dana-Farber Cancer Institute, returns to Patient From Hell to explain the ASCENT-04/KEYNOTE-D19 study, the phase 3 trial she led as principal investigator, and what it changes for people living with metastatic triple-negative breast cancer.For years, the most effective drugs for metastatic TNBC were only available after first-line chemotherapy had already failed. The problem, as Dr. Tolaney puts it plainly, is that many patients never reach a second line of treatment at all. ASCENT-04 asked whether moving an antibody-drug conjugate to the front, paired with immunotherapy, would change that. Median progression-free survival improved from 7.8 months to 11.2 months, and treatment responses lasted significantly longer.


    UPDATE: Since this recorded conversation, the FDA has acted on the data discussed in this episode. On May 22, 2026, Datopotamab Deruxtecan was approved for first-line metastatic TNBC in patients who are not candidates for immunotherapy. On June 24, 2026, Sacituzumab Govitecan was approved for first-line use both as a single agent and in combination with pembrolizumab for PD-L1-positive disease (CPS ≥10). Consult with your care team for the most recent indications and availability of these treatment options.


    00:00 The trial that moves the best drugs first

    00:31 Welcome back, Dr. Sara Tolaney

    00:40 What ASCENT-04 set out to solve

    02:00 Why many patients never reach second-line treatment

    02:50 What PD-L1 status means for your treatment

    04:12 The result: 7.8 to 11.2 months

    05:29 What is an antibody-drug conjugate (ADC)?

    06:33 Why TROP-2 is the target in triple-negative breast cancer

    07:24 How immunotherapy works: taking the brakes off the T cell

    09:01 Who was eligible for the trial

    10:05 What "controlling" cancer actually means

    11:44 Progression-free survival vs. duration of response

    13:37 Dr. Tolaney reconsiders: what ASCENT-03 showed

    15:51 How trial data reaches your oncologist's office

    18:21 The testing checklist after a metastatic diagnosis

    19:59 First-line treatment options today

    22:27 The new paradigm: ADCs as the first-line backbone

    23:51 What comes second line

    25:29 Why tumor sequencing matters: somatic BRCA, TMB, trials

    27:24 Twenty years of change in triple-negative breast cancer

    29:28 Advice for a newly diagnosed patient


    Sara M. Tolaney, MD, MPH is Chief of the Division of Breast Oncology and Associate Director of the Susan F. Smith Center for Women's Cancers at Dana-Farber Cancer Institute, and Associate Professor of Medicine at Harvard Medical School. She trained at Princeton University, UC San Francisco, Johns Hopkins University, and Dana-Farber Cancer Institute, and holds a Masters in Public Health (MPH) from Harvard University. She serves on the National Cancer Institute (NCI) Breast Cancer Steering Committee and is Vice Chair for Late-Stage Development in Breast Cancer for the Alliance for Clinical Trials in Oncology. She was principal investigator of ASCENT-04.


    🔗 Connect with Patient From Hell

    Website: https://www.mantacares.com


    Disclaimer

    This podcast is intended for educational and informational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional regarding diagnosis, treatment, or medical decisions.

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    32 min
  • “If You Have Lungs, You Can Get Lung Cancer” | Early Detection, Screening Cost & Stigma | Shira Boehler
    Jul 31 2026

    Shira Boehler's family is full of doctors, and every one of them told her not to get the full-body MRI. She canceled the appointment repeatedly herself, until her husband rebooked it one time too many and she finally went.


    The scan found a 3.8 centimeter mass in her right lung and labeled it a minor finding, with a note to correlate with symptoms. She had none. She was running six miles a day, the picture of health, and had never smoked. A follow-up CT months later showed the mass had grown, and on the Monday she walked into a pulmonary specialist's office she was told she had an invasive adenocarcinoma. She told him it was probably an EMR error. One week later, surgeons removed half her right lung to treat her cancer.


    Samira Daswani, host of Patient from Hell and founder of Manta Cares, welcomes lung cancer survivor and bestselling author Shira Boehler for an eye-opening conversation on the part that comes after the story, which is why almost nobody in Shira's position gets caught this early. Screening guidelines currently cover people over 50 with a twenty-pack-per-year smoking history, and fewer than one in five of them actually get scanned, in part because the criteria require disclosing something patients are ashamed of. Shira has been working the problem from both ends since her treatment, negotiating cash prices at imaging centers down to a fraction of what she paid and funding new scans for people who can't cover them through the nonprofit organization she founded, Cancer Doesn't Care.


    In this episode, Samira and Shira discuss:

    • Why lung cancer is often diagnosed too late

    • The importance of early detection and low-dose CT screening

    • How people who have never smoked can still develop lung cancer

    • The stigma surrounding lung cancer diagnosis

    • Current lung cancer screening guidelines

    • Insurance coverage, healthcare access, policy reform

    • How artificial intelligence may improve cancer screening

    • Why patient advocacy is becoming increasingly important in modern healthcare


    Chapters

    00:00 Introduction

    01:00 The Full-Body Scan That Changed Everything

    03:32 Diagnosed With Lung Cancer Despite Having No Symptoms

    05:30 Access, Privilege & Why Early Detection Isn't Equal

    07:10 Building the Cancer Doesn't Care Foundation

    09:21 Why Lung Cancer Screening Needs to Change

    10:19 Breaking the Stigma Around Lung Cancer

    12:26 Who Actually Qualifies for Screening?

    14:23 Changing Public Perception Through Advocacy

    16:20 Why Patients Must Advocate for Themselves

    17:15 AI, False Positives & the Future of Cancer Screening

    20:27 Why Lung Cancer Is Often Diagnosed Too Late

    21:17 Stage 1 vs. Stage 4 Survival Rates

    23:25 Shira's Advice for Anyone Considering Lung Cancer Screening


    Shira Kupperman Boehler is a finance professional, health advocate, bestselling author, and lung cancer survivor. Shira holds a degree in Molecular and Cell Biology from the University of California, Berkeley, and an MBA from New York University’s Stern School of Business. Alongside her husband Adam, she has spent her career building and scaling multibillion-dollar healthcare businesses, developing deep relationships across health systems, payers, and policymakers.
    After being unexpectedly diagnosed with Stage 1B lung adenocarcinoma despite never smoking and having no symptoms, Shira founded Cancer Doesn't Care, a nonprofit dedicated to expanding access to life-saving lung cancer screening and reducing financial barriers to early detection. She is also the author of the bestselling memoir One Scan Saved My Life, with proceeds supporting patient screening initiatives.


    🔗 Connect with Patient From Hell

    Website: https://www.mantacares.com


    Disclaimer

    This podcast is intended for educational and informational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional regarding diagnosis, treatment, or medical decisions.

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    26 min
  • Living Six Years with Stage 4 Lung Cancer | In Memory of Natalie Brown
    Jul 22 2026

    This episode is dedicated to Natalie's memory and to every patient navigating life with cancer.


    Natalie Brown's answer to "How are you?" was always simple:

    "I'm here."


    Diagnosed with stage 4 non-small cell lung cancer at just 33 years old, despite never smoking and having no family history of lung cancer, Natalie spent six years challenging assumptions about what lung cancer looks like.


    In this unforgettable conversation with host Samira Daswani, Natalie shares her journey through multiple rounds of chemotherapy, immunotherapy, failed clinical trials, and one of the rarest procedures in cancer medicine a bilateral double lung transplant. She also opens up about recurrence, chronic pain, advocacy, mental health, and why she believed every patient deserves to know all of their treatment options.


    Natalie has passed away. We are honored to share her story again in celebration of the courage, honesty, humor, and determination that defined her life. Her voice continues to educate, inspire, and advocate for patients everywhere.


    Whether you're living with cancer, supporting someone who is, or simply want to better understand the realities of serious illness, Natalie's message is one everyone should hear.


    In this episode you'll learn:

    • What it's like to be diagnosed with stage 4 lung cancer at age 33
    • Why non-smokers can develop lung cancer
    • How a rare double lung transplant became a treatment option
    • The emotional reality of cancer recurrence
    • Clinical trials, targeted therapies, and asking "What's next?"
    • The importance of patient advocacy and second opinions
    • How friends, family, therapy, and hope helped Natalie keep fighting
    • Why "Anyone with lungs can get lung cancer"


    Natalie's story reminds us that resilience isn't about pretending things aren't difficult—it's about continuing to move forward anyway.


    00:00 Introduction: Remembering Natalie Brown

    01:00 "I'm Here" — The phrase that defined Natalie

    02:00 Diagnosed with Stage 4 Lung Cancer at 33

    04:00 Four Chemotherapies & Failed Clinical Trials

    05:30 Discovering a Rare Double Lung Transplant

    10:40 Returning Home After Transplant

    11:45 Cancer Recurrence & New Treatment Options

    13:00 The Husband Who Helped Her Keep Fighting

    16:00 Facing Mortality with Honesty

    18:00 Making the Most of Time

    20:00 Living with Chronic Pain

    21:00 Becoming a Lung Cancer Advocate

    24:00 Learning to Ask for Help

    26:45 Advice for Newly Diagnosed Patients

    28:40 "Anyone With Lungs Can Get Lung Cancer"

    29:45 Why Patients Should Always Ask Questions

    31:00 Final Reflections


    About Patient From Hell


    Patient From Hell is hosted by cancer survivor and founder Samira Daswani, who asks the questions most patients are too overwhelmed or too afraid to ask. The show brings together doctors, researchers, advocates, and survivors to reveal evidence-based answers for patients navigating the chaos of cancer.


    🔔 Connect & Follow


    Samira Daswani

    LinkedIn: https://www.linkedin.com/in/samiradaswani/

    Manta Cares: https://www.mantacares.com


    Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard, or delay in obtaining, medical advice for any medical condition they may have, and should seek the assistance of their health care professionals for any such conditions.

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    32 min