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Metabolism Made Easy

Metabolism Made Easy

De : A J Ghalayini Ph.D.
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This podcast describes selected biochemistry content that could be useful to premedical/medical students. Similar content (podcasts and videos) is available at: https://medbiochem.org/ or check out my YouTube channel: Metabolism Made Easy These podcasts and videos cover selected topics in medical biochemistry. A J Ghalayini, Ph.D. Bio for Dr. Ghalayini: Dr. Ghalayini received his Ph.D. in Biochemistry from the University of Houston, Houston, Texas. He has over 3 decades of experience in research and medical education as professor of biochemistry at 5 different universities.A J Ghalayini, Ph.D.
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    Épisodes
    • Pyruvate: Distinct Roles During Fasting/ Well-Fed States- AI Podcast
      Jan 27 2026

      This podcast explains how the human body adapts its metabolic pathways to manage pyruvate based on its nutritional status. In the well-fed state, high glucose levels allow pyruvate to fuel the TCA cycle for energy or assist in creating nonessential amino acids. Conversely, during fasting or physical exertion, the body shifts toward gluconeogenesis to synthesize new glucose from available resources. This process involves converting substances like lactate and alanine from the muscles back into pyruvate within the liver. Ultimately, the source highlights the body’s metabolic flexibility in maintaining energy balance through varying physiological conditions.



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      15 min
    • 8 Enzymes Regulated by Insulin
      Jan 19 2026

      Insulin binding to its receptor initiates a cascade of intracellular events that lead to the activation of a phosphoprotein phosphatase. This phosphatase will dephosphorylate 8 distinct enzymes involved in carbohydrate and lipid metabolism and change their activity, thus changing the overall metabolism of carbohydrates and lipids.

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      3 min
    • Allosteric Regulation of Enzymes
      Jan 11 2026

      In this short, the effect of allosteric effectors on enzyme kinetics is covered in some detail including the effect of allosteric effectors on either Vmax or the the enzyme's affinity for its substrate.

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      3 min
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