Episode 21 - Optimizing Therapy Over Time: Route Selection and Titration
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This module focuses on translating PAH treatment strategy into an individualized, sustainable regimen by considering route of administration, titration, tolerability, and treatment burden. It examines the practical differences among oral, inhaled, subcutaneous, and intravenous therapies and how disease severity, treatment response, adverse effects, patient preferences, and capacity for self-management influence therapeutic choices. The module also emphasizes proactive adverse-event management, individualized titration, frequent reassessment, patient education, and multidisciplinary support to promote treatment persistence while continuing to pursue appropriate risk-based treatment goals.
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