Young mother Brenda DuPont is found murdered in her home in Opelousas, Louisiana in May 1988. The initial investigation quickly turns cold, but Brenda’s older sister, Linda, vows to get justice, no matter how long it takes.

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A man suspected of the cold case murder of his wife and son hatches a new plot to kill his mother and father; and detectives solve the 20-year-old murder of a teenager by tricking her killer into licking an envelope, then extracting DNA from the saliva.

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In November of 1986, 25-year-old Josephina Rivera's life comes to a devastating halt when she's kidnapped by 43-year-old Gary Heidnik. Over the next four months, Josephina lives shackled in a basement while her captor abducts four more women to hold hostage in his "house of horrors." Josephina recounts a gripping tale of endurance and the shrewd calculations that helped her devise a plan of escape.

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Three-year-old Vanessa Bennett becomes the lone survivor of her family’s brutal massacre in early 1984. Investigators at the time suspect that a serial killer is at large, but decades later the suspect pool narrows down to just one man.

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The dogged work of an Alberta, Canada, detective finally pays off when he tracks down the man who raped and murdered a 6-year-old girl 10 years earlier. And when police search for the killer of an 18-year-old hitchhiker, they find that the victim's diary is one of their best clues.

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Survivor Morgan Rowan describes for the first time on television how she was brutally attacked in 1968 by social gadfly Rodney Alcala, during a party at his Hollywood home. Just three weeks later, Alcala would abduct and attack 8-year-old Tali Shapiro, who describes her chilling assault in her own words. Morgan and Tali were the only survivors of soon to be serial killer Rodney Alcala, who was convicted of five Southern California murders in the 1970's. Alcala was so wickedly brazen that he actually appeared on an episode of "The Dating Game" during his murderous reign of terror.

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A promise is sacred in North American Indigenous Cree culture, and when Cree woman Shirley Soosay vanishes in 1980, her niece, Violet, promises her grandmother that she will bring Shirley home. But, Violet never imagined that the search for her aunt, and justice, would take a lifetime.

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Klan leader Sam Bowers goes on trial for ordering the murder of an African-American storeowner 32 years prior, and investigators reopen the unsolved case of an African-American truck driver who was forced to leap to his death from a bridge by Klan members.

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